The role of genome reorganisation in adaptation and speciation

局部适应和物种形成是依赖于基因组变化的基本进化过程。然而，基因组结构（如染色体重排，基因复制）在驱动这些过程中的作用知之甚少。本项目将使用先进的比较基因组学和生物信息学来研究染色体重排在驱动适应和物种形成中的作用，并评估x染色体和常染色体之间的分子进化速率。利用澳大利亚特有的哺乳动物群作为一个可处理的模型系统，我将把种群过程与宏观进化结果联系起来，以展示基因组结构如何支撑生物多样性。

Local adaptation and speciation are fundamental evolutionary processes that rely on changes to the genome. However, the role of genome architecture (e.g. chromosomal rearrangements, gene duplications) in driving these processes is poorly understood. This project will use advanced comparative genomics and bioinformatics to examine the role of chromosome rearrangements in driving adaptation and speciation, and evaluate rates of molecular evolution between the X-chromosome and autosomes. Utilising Australia’s endemic mammalian fauna as a tractable model system, I will link population processes with macro-evolutionary outcomes to show how genome architecture underpins biodiversity.