Pathogenesis and treatment of gonarthrosis spatial aspect on the thrust of osteoarthritic knees.

在行走时对正常膝关节和骨关节炎膝关节进行了加速测量和足部压力分析。侧向升高的楔形鞋垫可以降低侧向加速度的大小，同时增加足底压力中心的内侧长度。因此，该鞋垫对于保守治疗内侧间隙CA膝关节是有效的。然而，根据生物力学和放射学分期分析鞋垫的治疗效果时，这种鞋垫疗法在年龄较小的患者中使用较少。因此，这些发现表明鞋垫疗法并不适用于所有个体。我们通过关节音来评估透明质酸治疗严重骨性关节炎的效果。研究对象为40例终末期骨性关节炎患者的40个膝关节，男8例，女32例，平均年龄66.7岁。曾给他们注射过一次HA。在膝关节注射前后，分别在关节弯曲和伸展时测量关节音5次。用Bruel&Kjaer 4189型麦克风记录声音，输入双通道分析仪，进行快速傅立叶变换频谱分析。HA给药前平均频率为422.5×68.9赫兹，给药后即刻为219.4×22.9赫兹，频率显著降低。对照组给药后与给药前相比无显著差异。说明关节内注射透明质酸具有一定的润滑作用。

Accelerometric and foot pressure analyses were performed on normal and osteoarthritic knees while walking. A laterally elevated wedged-insole was found to decreasa the magnitude of the lateral accelcration while increasing the medial length of the center of foot pressure. The insole thus proved effective for the conservative treatment of the medial compartment CA knees. However, when analyzing the therapeutic efficacy of the insole according to the biomechanical and radiographic stage, use of such insole therapy proved to be less in obase patients. These findings thus suggest that insole therapy is not appliciable to all individuals.We evaluated the effect of hyaluronic acid on severe osteoarthritis by joint sound. The subjects were 40 knees of 40 end stage OA patients (8 male, 32 female) with a mean age of 66.7 years. HA was administered to them once. Before and after the injection into the knee joint, we measured joint sounds 5 times while bending and stretcing the joint. The sound were recorded by Bruel & Kjaer 4189 type microphones and input into a 2 channel analysis device, and then the fast fourier transformed frequency spectru** was analyzed. The mean frequency before HA administration was 422.5*68.9Hz, and 219.4*22.9Hz immediately after, indicating a significant decrease in frequency. There was no significant difference seen in the control group after administration. This showed that injection of HA in to the knee joint had a lubricating function.