ACTIVATION OF METALS AND THEIR UTILIZATION FOR ORGANIC SYNTHESIS

随后的立体声有机转化是用活性的锰物质或铬开发的（II）。（1）1-iodoalkyl triethlsilyl ether的治疗，衍生自an alkanal and Ety D23 yie D2SiI in dichlorometane， with a mixture of manganese and PbCI yie D22 yie D2 in THF generates a nonstabilized carbonyl ylide。通过[3+2]环肾上腺素反应与不饱和的化合物、如α、β-不饱和的esters、allylic ethers和aldehyde给予四氢呋喃衍生物（或二氧烷）。（2）微相对性铬（II）氯化物可以在烷基碘化、烷基基在铬（II）的存在中，烷基基本体的寿命如此长，以至于它可能是一种潜在的互分子添加到1，3-diene。快速的一个电子减少了在一种合金铬物种中形成的合金自由基结果，其中添加了一种替代品，从而产生了三个分量耦合产品。（3）α-chloroalkylboronic esters与CrCI-D22-D2在LiI和TMEDA产生α-boryl radicals中的治疗，其中添加到α， β-不饱和的esters在优秀年份中的1，4-时尚条件下。（4） A chromium hydride equivalent generated from CrCI-D22-D2， B-D212-D2， and water reacts regioselectively with 1，3-dienes to give allylic chromium reagents， and the reagents add to carbonyl compounds in a chemo-and stereoselective maner。（5）在醛到（E）-1-碘醇的立体声转化中的铬盐的催化循环，用锌、Mey D23 y D2 SiCI和Dioxane中的NaI组装。（6） Iodoform is reduced with manganese in the presence of Me的D23的D2 SiCI to give Me的D23的D2 SiCHI的D22的D2。一个从一罐到（E）-1-烯基三甲基硅烷转化为一罐，然后以碘形式、芒果、Me-D23-SiCI和一个催化量的铬（II）THF中的氯化物通过我的原位形成-D23-D2 SiCHI-D22-D2-D2-D2-D2。

The following stereoselective organic transformations have developed with an activated manganese matal or chromium (II). (1) Treatment of 1-iodoalkyl triethlsilyl ether, derived from an alkanal and EtィイD23ィエD2SiI in dichloromethane, with a mixture of manganese and PbCIィイD22ィエD2 in THF generates a nonstabilized carbonyl ylide. The ylide reacts with unsaturated compounds, such as α, β-unsaturated esters, allylic ethers, and an aldehyde, to give tetrahydrofuran derivatives (or a dioxolane) via [3+2] cycloadditon reactions. (2) The mild reluctant chromium (II) chloride can discriminate between alkyl iodides, alkyl radicals, and allylic radicals. In the presence of chromium (II) the alkyl radical is so long-lived that it can undergo intermolecular addition to a 1, 3-diene. Rapid one-electron reduction of the formed allylic radical results in an allylic chromium species, which adds to an aldehyde to afford a three-component coupling product. (3) Treatment of α-chloroalkylboronic esters with CrCIィイD22ィエD2 in the presence of LiI and TMEDA generates α-boryl radicals, which add to α, β-unsaturated esters in a 1, 4-fashion under mild conditions in excellent yields. (4) A chromium hydride equivalent generated from CrCIィイD22ィエD2, BィイD212ィエD2, and water reacts regioselectively with 1, 3-dienes to give allylic chromium reagents, and the reagents add to carbonyl compounds in a chemo- and stereoselective manner. (5) A catalytic cycle of a chromium salt in a stereoselective transformation of aldehydes to (E)-1-iodoalknens using a geminal dichromium reagent, is assembled with zinc, MeィイD23ィエD2SiCI, and NaI in dioxane. (6) Iodoform is reduced with manganese in the presence of MeィイD23ィエD2SiCI to give MeィイD23ィエD2SiCHIィイD22ィエD2. A one-pot transformation of aldehydes to (E)-1-alkenyltrimethylsilanes is then performed with iodoform, manganese, MeィイD23ィエD2SiCI, and a catalytic amount of chromium(II) chloride in THF via in situ formation of MeィイD23ィエD2SiCHIィイD22ィエD2.