Intelligent screening of Mycobacterium avium paratuberculosis (MAP) in dairy cattle

副结核或约翰氏病是一种牛的疾病，具有很高的经济和动物福利成本。由于禽副结核分枝杆菌（MAP）可能是人类克罗恩病的一种可能原因，大多数畜群每季度对个别奶牛进行检测。然而，不幸的是，对牛奶样本进行的常规检测既昂贵又经常不准确。在本研究中，我们将测试挥发性有机化合物（VOC）分析在牛乳和粪便样本顶空中的可行性，以检测可行MAP的存在，并将该技术小型化到便携式设备中。

Paratuberculosis or Johne's disease is a disease of cattle with a high financial and animal welfare cost. Quarterly testing of individual cows is performed in most herds as the bacteria _Mycobacterium avium paratuberculosis_ (MAP) may be a possible cause of Crohn's disease in humans. Unfortunately, however, the routine testing performed on milk samples is both costly and often inaccurate. In this study we will test the feasibility of Volatile Organic Compound (VOC) analysis in the headspace of bovine milk and faecal samples to detect the presence of viable MAP and miniaturize the technology into a portable device.