Feasibility studies of SMILE (SMart Last-mILE cooling system) for the developed world

根据世界卫生组织的数据，在新冠肺炎之前，全球仍有2000万儿童无法获得基本的疫苗接种，每年有200万至300万儿童死于疫苗可预防的疾病。在全球范围内，20%-50%的疫苗被浪费，在偏远地区，据报道85%的疫苗变质。其中一个原因是，在运送的最后几英里(“最后一英里”)，疫苗会被温度波动损坏。然而，现场使用的疫苗载体本质上是凉爽的盒子，即装满冰袋的盒子。它们要么冷冻疫苗，要么在使用中只能维持一天。此外，人为错误和不正确的处理进一步加速了腐败。IDEABATIC的成立是为了在资源有限的偏远地区解决这些最后一英里的冷链问题。我们创造了SMILE，这是一种获得专利的智能最后一英里冷却系统，可以最大限度地减少人为错误，减少损坏并提高效率。一位资深科学家将其描述为一台“星际迷航：疫苗机器”。微笑就像一台坚固的、带着背包的便携式疫苗自动售货机，专为穿越崎岖的地形而设计。它是低技术含量的，而且不会犯傻。SILE形状为六边形，包含一个圆柱形冰块，周围环绕着一个容纳疫苗瓶子的旋转木马系统。旋转木马也是一个空气锁系统。自动关闭的门与旋转木马相辅相成，即使在门反复打开的情况下，也能最大限度地减少热量传递。在不通电的情况下，微笑可以持续3-6天，同时监控和展示剩余的酷炫生活。SILE已经过反复测试、实验室测试和现场测试。我们于2019年在马达加斯加的偏远村庄进行了一次成功的试验。微笑将有助于最后一英里的应用，但不仅限于发展中国家。在全球范围内，冷盒被用于研究机构、生物医药公司和物流公司，在这些公司，类似的问题仍然存在。我们的创新解决方案需要评估，以了解它与发达国家客户及其工作环境的需求的兼容性。该项目的目的是调查发达国家(成熟)市场中SILE可能产生影响的选定地区，并通过合作探索国际合作伙伴关系和进入新市场。我们最近采访了阿联酋、日本和台湾对SILE表现出兴趣的公司。我们希望将重点放在这些地区进行评估，以加强我们的服务并确定进入市场的主要途径。我们的最终目标是提高以下方面的效率：*疫苗覆盖率(包括新冠肺炎)*样本采集*研究*冷链应用*通过在全球范围内使用SILE或其相关技术。

According to the WHO, pre-COVID-19, 20 million children worldwide still had no access to basic vaccinations and 2 to 3 million children died each year of a vaccine-preventable disease. Globally, 20-50% of vaccines are wasted and in remote areas, 85% spoilage has been reported. One of the reasons is that during the last few miles of delivery ('last-mile') vaccines become damaged by temperature fluctuations .However, vaccine carriers used in the field are essentially cool boxes, i.e. boxes filled with icepacks. They either freeze vaccines or last barely a day when in use. Moreover, human error and incorrect handling further accelerate spoilage.IDEABATIC was established to solve these last-mile cold-chain issues in remote areas with limited resources. We created SMILE, a patented, SMart, last-mILE cooling system that minimises human error, reduces spoilage and improves efficiency. A senior scientist described it as a "Star Trek vaccine machine". SMILE is like a robust, portable vaccine vending machine with a backpack, designed for travel over rugged terrain. It is low-tech and fool-proof. Hexagonal in shape, SMILE contains a cylindrical ice block surrounded by a carousel system that holds vaccine vials. The carousel is also an air-locking system. A self-closing door complements the carousel to minimise heat transfer even when the door is opened repeatedly. SMILE can last for 3-6 days without power while monitoring and displaying the remaining cool-life. SMILE has been iterated, lab tested and field tested. We conducted a successful trial in remote villages in Madagascar in 2019\.SMILE will help in last-mile applications but is not limited to use in developing countries. Globally, cool boxes are used in research institutions, biomedical companies and logistics companies where similar issues persist. Our innovative solution requires evaluation to appreciate how compatible it is with the needs of developed-world customers and their working environments.The aims of this project are to investigate selected regions in the developed-world (mature) market where SMILE could make an impact and to explore international partnerships and gain access to new markets through collaboration.We recently spoke to companies in the UAE, Japan and Taiwan who have shown an interest in SMILE. We wish to focus on these regions for evaluation to strengthen our offering and identify the primary route to market.Our ultimate goal is to improve efficiency in:* vaccine coverage (including COVID-19)* sample collection* research* cold-chain applicationsby using SMILE or its related technologies globally.