Peptide insecticides: new targets and commercialisation

SOLASTA Bio为全球粮食作物害虫破坏问题提供了突破性的解决方案，目前传统杀虫剂受到可持续性和环境问题的困扰。我们的肽（小蛋白）杀虫剂针对昆虫生理学的独特特征，为粮食作物提供安全有效的害虫控制。这些新的生物杀虫剂不伤害贝内？如果在市场上取得成功，将取代目前的合成化学品，增加对环境和终端消费者健康的管理。对大型化合物库进行高效而耗时的随机筛选，传统的发现程序需要花费长达三年的时间，此外还具有对害虫的内在安全性以及对新害虫目标的快速和灵活性。在这个为期18个月的A系列项目中，我们将生命科学和化学领域的新创新与研发和商业团队的发展结合起来，以实现：* 将我们的发现平台转向新的目标和市场;* 提高内部肽合成、配方和低碳肽合成路线的能力;* 针对新市场在内部和外部评估候选药物的功效和毒性。我们还将：* 为业务提供碳审计/路线图;* 制定监管路线图。

SOLASTA Bio provides a disruptive solution for the global problem of destruction of food crops by insect pests, where current conventional insecticides are beset with sustainability and environmental problems.Our peptide (small protein)-based insecticides target a unique feature of insect physiology to provide safe, effective insect pest control for food crops. These new bioinsecticides do not harm bene?cial insect species and if successful in the market, will replace current synthetic chemicals, increasing stewardship of the environment and end-consumer health.Our innovative, targeted discovery platform does away with the costly, inef?cient and time-consuming random screening of large libraries of compounds which consumes up to three years in a traditional discovery program, with the added advantage of built-in safety to beneficials; and speed and agility for new pest targets.In this 18-month Series A project addressing Net Zero, we bring together new innovations across the life sciences and chemistry together with R&D and commercial team growth to:* pivot our discovery platform to new targets and markets;* increase in-house capacity for peptide synthesis, formulations and reduced-carbon peptide synthesis routes;* evaluate candidate efficacy and toxicity in-house and externally, for new markets.We will also:* deliver a carbon audit/roadmap for the business;* establish regulatory roadmaps.