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中文摘要
翻译
行政核心的总体目标是提供一个强有力的中央行政结构, 协调拟建的NCTRI西北子宫肌瘤中心研究人员和 提供运营支持,以减轻其调查人员的负担,使他们能够专注于 研究。核心将确保拟议的中心实现其目标,并将协同 研究项目调查员与教育和外展核心以及组织采购的工作 和细胞培养核心。行政核心将协调研究项目的参与 参与教育和外联核心的社区参与和研究培训活动的调查员。 我们已经开发了一个组织结构最优的组织/细胞核心,由经验丰富的妇科病理学家运营,以 支持西北大学的光镜研究;这将为获取和储存组织提供有效的设施 用于细胞制备和储存的样品。这一设施完全由以下机构的内部资金支持 西北大学。行政核心将确保和协调将人体组织和细胞分配到 所有中心调查人员。核心还将征求和协调试点项目的严格审查程序 申请。以下是行政核心的目标,这些目标体现了总体目标。目标1.减少 通过提供资金和资源在中心研究项目内部和之间设置行政障碍 管理服务。目标2.通过已建立的沟通方法培养团队科学 整合跨学科研究,协调中心内外的科学工作。目标3. 提供一个行政框架,以评估研究项目和核心的进展情况,以确保 加快高质量研究步伐,征集试点项目申请,严格遴选最佳试点 项目。所有目标将通过核心主任、布伦博士和研究人员的努力实现 行政长官艾琳·辛普森,他将提供全面和全面的行政支持。目标1是 旨在为调查人员、项目和人员提供财务和人力资源管理支持 核心;布伦和辛普森团队将担任NIH和西北大学中央办公室的联络人。目标 2将通过一系列沟通努力来完成,包括定期召开研究会议 进度和沟通更新以及研究项目和核心职能的协调。目标3 将支持审查每个项目进展情况的内部和外部咨询委员会的努力 并对整个中心提供反馈,并帮助审查试点项目的申请并选择最佳方案 试点项目。通过这些活动协调中心,行政核心将确保不受限制的 中心研究的进展,利用团队科学和跨学科的努力来加快步伐 发现,并评估进展和轨迹,使中心始终在目标上。
英文摘要
The overall goal of the Administrative Core is to provide a robust centralized administrative structure that will coordinate the activities of the proposed NCTRI Northwestern Uterine Leiomyoma Center researchers and provide operational support that will reduce the burden on its investigators, allowing them to focus on their research. The Core will ensure that the proposed Center achieves its aims and will synergize the efforts of the Research Project investigators with the work of the Education and Outreach Core and the Tissue Procurement and Cell Culture Core. The Administrative Core will coordinate the participation of the Research Project investigators in the community engagement and research training activities of the Education and Outreach Core. We have developed an optimally organized Tissue/Cell Core, run by an experienced gynecologic pathologist to support LM research at Northwestern; this will provide an efficient facility for procuring and banking tissue samples and for cell preparation and storage. This facility is entirely supported by intramural funds from Northwestern. The Administrative Core will ensure and coordinate the distribution of human tissues and cells to all Center investigators. The Core will also solicit and coordinate a rigorous review process for Pilot Project applications. Below are the aims of the Administrative Core, which capture the overall objectives. AIM 1. Reduce administrative barriers within and between Center Research Projects by providing funds and resource management services. AIM 2. Foster team science through established communication methodologies to integrate cross-disciplinary research and coordinate scientific efforts within the Center and externally. AIM 3. Provide an administrative framework to evaluate the progress of the Research Projects and the Cores to ensure a rapid pace of high-quality research and to solicit Pilot Project applications and rigorously select the best Pilot Project. All aims will be achieved through the efforts of the Core Director, Dr. Bulun and the Research Administrator, Erin Simpson, who will provide overall and comprehensive administrative support. Aim 1 is designed to provide support for financial and human resources management for the investigators, projects and cores; the Bulun and Simpson team will serve as the liaison to NIH and to central offices at Northwestern. Aim 2 will be accomplished through a series of communication efforts, including recurring meetings for research progress and communication updates and the coordination of the Research Projects and Core functions. Aim 3 will support the efforts of the Internal and External Advisory Committees that will review each project's progress and provide feedback on the overall Center and help review the Pilot Project applications and select the best Pilot Project. By aligning the Center through these activities, the Administrative Core will ensure the uninhibited progress of the Center's research, leverage team science and cross-disciplinary efforts to accelerate the pace of discovery, and evaluate progress and trajectory so the Center is consistently on target.
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会议论文
Estrogen, Astrocyte Reactivity, and Sex Differences in Alzheimer's Disease
Environmental Pollutants and AHR pathway in Uterine Leiomyoma
Gut Microbiome and Steroid Hormones
  • 批准号:
    10054472
  • 项目类别:
  • 资助金额:
    $20.45万
  • 财政年份:
    2020
  • 负责人:
    Serdar E. Bulun
  • 依托单位:
Epigenome, MED12 and Progesterone Action in Uterine Leiomyomas
海外基金