CBEC-KEMRI BIOETHICS TRAINING INITIATIVE

摘要 低收入和中等收入国家的人体研究呈指数级增长 (LMIC)在过去20年中并没有伴随着相应的增长 训练有素的生物伦理学家，导致研究监管的严重缺口。肯尼亚有22个认证机构 院校研究伦理委员会(IREC)，每个委员会有10-15名成员。为了解决这个问题， 肯尼亚医学研究所(KEMRI)与生物医学中心合作 巴基斯坦卡拉奇的伦理与文化(CBEC)寻求加强生物伦理的能力 通过建立CBEC-KEMRI生物伦理培训在两国开展培训 计划(CK-BTI)，提供生物伦理学硕士(MBE)、研究生文凭(PGD)和 生物伦理学证书课程。具体而言，这一协作培训倡议将培训核心 肯尼亚教员(目标1)，为肯尼亚培训核心教员：为 可持续方案，(目标2)为以下目标建立创新和协作的生物伦理学课程 肯尼亚(目标3)在当地提供研究生文凭和伦理学硕士学位 课程(目标4)通过提供证书课程和 设计实践，其中包括如何管理REC的实践经验 肯尼亚和巴基斯坦的区域经济共同体成员秘书处。根据CK-BTI，总共有350个 肯尼亚学员将接受如下培训：8名MBE学员、22名PGD学员和320名学员 证书参与者。此外，30名巴基斯坦学者，包括10名MBE候选人和20名 与CBEC相关的参与者将在KEMRI进行实践，以丰富他们的实践 利用不同文化背景的研究环境以及 提高他们在忙碌的IRB办公室中的实际操作技能。CK-BTI将提供三个独特的 和创新特点：包含远程学习组成部分的模块化培训 适合不同的申请者基础，在KEMRI科学和伦理学的实践经验 审查单位(SERU)，旨在影响各委员会和IRB秘书处的职能；以及 最后，提供丰富的跨文化生命伦理体验。这项计划的目标是参与者 来自医学研究领域的医疗保健专业人员、区域经济共同体成员和来自 不同的背景，这将确保广泛的高等教育机构，以及 肯尼亚和巴基斯坦的区域经济共同体从培训中受益。我们计划开发一个临界量的 训练有素的专业人员、学者、研究科学家和其他卫生专业人员 肯尼亚和巴基斯坦，对道德考量、概念有深入和实际的了解 和在社会、生物医学、临床和公共卫生研究领域的应用，以及谁将 影响他们的机构，成为各自国家的生物伦理领袖。

Abstract An exponential increase in human subjects research in low and middle income countries (LMIC's) in the last two decades has not been accompanied by a commensurate increase in trained bioethicists, resulting in a critical gap for research regulation. Kenya has 22 accredited Institutional Research Ethics Committees (IREC) each with 10-15 members. To address this, the Kenya Medical Research Institute (KEMRI) in partnership with the Centre for Biomedical Ethics and Culture (CBEC) in Karachi, Pakistan, seek to strengthen capacity for bioethics training in the two countries through the establishment of the CBEC-KEMRI Bioethics Training Initiative (CK-BTI), that offers a Masters in Bioethics (MBE), Post- Graduate Diploma (PGD) and Certificate Courses in Bioethics. Specifically, this collaborative training initiative will train core faculty for Kenya (Aim 1), To train core faculty for Kenya: building initial bioethics capacity for a sustainable program, (Aim 2) To build an innovative and collaborative curriculum in bioethics for Kenya (Aim 3) To offer locally available Post Graduate Diploma and Masters in Ethics degree courses (Aim 4) To rapidly build capacity for review for REC by offering certificate courses and to design a practicum which includes hands on experience on how to manage an REC secretariat for REC members for both Kenya and Pakistan. Under the CK-BTI, a total of 350 Kenyan participants will be trained as follows: 8 MBE students, 22 PGD students and 320 certificate participants. In addition, 30 Pakistani scholars comprising 10 MBE candidates and 20 CBEC-linked participants will undertake a practicum at KEMRI to enrich their practical understanding of ethical issues using a culturally-diverse research environment, as well as enhance their hands-on skills in the running of a busy IRB office. CK-BTI will offer three unique and innovative features: modular training which encompasses a distance learning component suitable for a diverse applicant base, practical experience at the KEMRI Scientific and Ethics Review unit (SERU) designed to impact the function of committees and IRB secretariats, and lastly to provide a rich cross-cultural bioethics experience. This initiative will target participants from the medical research field, health care professionals, members of RECs and trainees from diverse backgrounds, which will ensure that a wide range of Institutions of higher learning, and RECs in Kenya and Pakistan benefit from the training. We plan to develop a critical mass of well-trained professionals, academics, research scientists, and other health professionals in Kenya and Pakistan with in-depth and practical knowledge of ethical considerations, concepts and applications in social, biomedical, clinical and public health research areas and who will impact their institutions and be leaders of bioethics in their respective countries.