The University of Rochester Clinical and Translational Science Award Hub

联系PD/PI：Zand，Martin S 核心O：总体-项目总结/摘要 临床和转化科学研究所（UR CTSI）是罗切斯特大学的研究引擎 医学中心UR CTSI催化了整个大学的研究，建立了一个强大的翻译 研究生态系统。在接下来的五年里，UR CTSI将专注于“没有围墙的转化研究”， 超越机构的物理和虚拟界限。我们将加快整合翻译 学习健康系统的研究。我们将扩大我们的创新传播方法， 实施（D & I）研究，包括：一个新的和专门的D & I KL2学者职位，一个健康公平 重点传播和实施可选功能;以及一个合作试点计划，重点 特别是学习健康系统内的D & I项目。我们将开发和传播小说 教育材料和方法。我们将创建一个转化研究数据生态系统， 通过连接我们的研究和临床数据仓库，整合整个翻译范围内的数据。我们 将实施ACT/SHRINE队列发现软件，并广泛使用健康数据中心 （CD2H）工具、本体和工作组。我们将在试点项目中扩大教育工作， 实现转化研究数据和卓越分析。我们将加强转化研究 在地方和国家两级，各利益攸关方之间开展协作。我们将继续 广泛参与CTSA协调中心。我们将把我们成功的计划扩展到 以社区为基础的参与性研究，促进与社区成员组成多学科团队。 我们将扩大我们的地方和国家合作。我们将培养下一代翻译 科学劳动力领导者，扩大我们的方法，以确保在协作，技术， 和必要的监管技能，以加快高影响力的研究转化为临床应用。我们 将开发和传播新的教育材料，研究人员的支持，和方法。我们将催化 制定、实施和传播促进发展的方法和程序， 在CTSA联盟的地方和全国范围内进行转化研究， 远程数据和样本收集;通过监管支持和行业加速基础和早期研究 赞助;和快速试验评估，谈判和批准的计划。我们将加强我们的参与者 和临床互动功能，以适应远程研究访视和远程数据和样本采集 方法.我们将利用我们现有的优势来实施和管理多中心研究。 页172 项目总结/摘要 联系PD/PI：Zand，Martin S CORE O.总体而言，

Contact PD/PI: Zand, Martin S CORE O: OVERALL – PROJECT SUMMARY/ABSTRACT The Clinical and Translational Science Institute (UR CTSI) is the research engine of the University of Rochester Medical Center. The UR CTSI has catalyzed research throughout the University, building a robust translational research ecosystem. During the next five years, the UR CTSI will focus on “translational research without walls,” moving beyond the physical and virtual confines of institutions. We will accelerate integration of translational research with the Learning Health System. We will expand our innovative approaches to dissemination and implementation (D&I) research including: a new and dedicated D&I KL2 scholar position, a Health-Equity Focused Dissemination and Implementation Optional Function; and a collaborative pilot program focused specifically on D&I projects within the Learning Health System. We will develop and disseminate novel educational materials and methods. We will create a translational research data ecosystem that seamlessly integrates data across the translational spectrum by linking our research and clinical data warehouses. We will implement the ACT/SHRINE cohort discovery software and make extensive use of Center for Data to Health (CD2H) tools, ontologies and working groups. We will expand education efforts across our pilot programs to achieve translational research data and analytic excellence. We will enhance translational research collaborations at the local and national levels across the spectrum of stakeholders. We will continue our extensive participation with the CTSA Coordinating Centers. We will extend our successful program in community-based participatory research, facilitating multidisciplinary team formation with community members. We will expand our local and national collaborations. We will educate the next generation of translational science workforce leaders, expanding our approaches to ensure competence in the collaborative, technical, and regulatory skills necessary to accelerate the translation of high impact research to clinical applications. We will develop and disseminate novel educational materials, investigator support, and methods. We will catalyze the development, implementation and dissemination of methods and processes that advance translational research locally and nationally across the CTSA Consortium through methods to advance remote data and sample collection; speeding basic and early stage research with regulatory support and industry sponsorship; and programs for rapid trial evaluation, negotiation, and approval. We will enhance our Participant and Clinical Interactions Function to accommodate teleresearch visits and remote data and sample capture methods. We will employ our existing strengths to implement and manage multi-site research studies. Page 172 Project Summary/Abstract Contact PD/PI: Zand, Martin S CORE O. OVERALL –