Chemistry-Biology Interface T32

德克萨斯大学西南医学中心(UTSW)在重视和推广方面有着悠久的制度历史 协作科学，并为化学和生物化学研究生提供了一个独特的环境 参与跨学科的教育和研究。这项建议体现了UTSW的文化和 概述了一个新的博士前培训计划，致力于在化学领域提供跨学科培训- 生物接口(CBI)。我们的培训计划以药物发现的心态组织起来，为年轻人提供装备 具备应对挑战所需的基础知识和跨学科技能的科学家 生物医学研究中的各种问题，并确定新的机会领域。作为一项指导原则，我们 相信建立一支强大和多样化的生物医学队伍需要在个人方面发展卓越 同时促进不同领域的专家之间的合作努力。学生完成严谨 在化学或生物方面的研究生培训，同时也发展最重要的 这两个领域的原则和问题。加州大学斯威夫特分校的CBI项目旨在实现三个目标：第一， 学生将成为各自领域的化学或生物专家。其次，学生们将成为 对这两个领域最重要的原则和问题了如指掌。最后，学生们将成为 擅长向广泛的个人传达科学挑战和发现，从专家到 门外汉。CBI计划将直接支持两名学生在博士前二年级和三年级学习 培训，还将培训由UTSW通过私人资金支持的McKnight研究员；所有受训人员 将继续受益于CBI的资源，直到毕业。该计划将利用其在一个 领导医学中心提供以临床前药物发现为重点的培训活动。培训人员 CBI项目的成员是支撑培训项目的丰富合作网络的一部分， 而且还延伸到整个大学和更大的科学界。总而言之，这些培训 Aspects旨在为学生提供工作中的科学知识和协作能力 共同组成一个跨学科团队，解决最紧迫和最棘手的科学问题， 培养下一代生物医学研究人员的目标。UTSW CBI的“增值”功能 培训方案包括：(A)由学术界专家讲授的药物发现高级课程 工业；(B)改进酶和疾病课程，促进跨学科和协作科学 通过同行领导的团队学习；(C)专门针对资金的科学写作的个性化指导 机会；(D)通过辅导性制作Science Sketch YouTube进行科学交流培训 视频；(E)受训人员设计参加迷你休假，以促进跨学科和非学术 培训；(F)CBI实习生与提供合校支持的教职员工咨询委员会之间的每月会议 (G)为教学和外联活动提供支助。

UT Southwestern Medical Center (UTSW) has a long institutional history of valuing and promoting collaborative science, and provides a unique environment for chemistry and biochemistry graduate students to participate in interdisciplinary education and research. This proposal embodies the culture of UTSW and outlines a new predoctoral training program dedicated to providing interdisciplinary training at the Chemistry- Biology Interface (CBI). Organized with a Drug Discovery mindset, our training program equips young scientists with the fundamental knowledge and interdisciplinary skills that are needed to tackle challenging diverse problems in biomedical research and to identify new areas of opportunity. As a guiding principle, we believe that building a strong and diverse biomedical workforce requires developing excellence in individual disciplines while fostering collaborative efforts among experts in disparate fields. Students complete rigorous graduate training in either chemistry or biology, while also developing broad knowledge of the most important principles and problems in both fields. The CBI at UTSW program is designed to meet three objectives: First, students will become experts in their individual fields of chemistry or biology. Second, students will be knowledgeable about the most important principles and problems in both fields. Finally, students will be skilled in communicating scientific challenges and discoveries to a wide range of individuals, from experts to laypeople. The CBI program will directly support two students each during years 2 and 3 of their predoctoral training and will also train McKnight fellows who are supported by UTSW through private funds; all trainees will continue to benefit from CBI resources until graduation. The program will capitalize on its setting within a leading medical center to offer training activities that focus on preclinical Drug Discovery. The training faculty members for the CBI program are part of a rich network of collaborations that scaffold the training program, but also extend throughout the University and into the larger scientific community. Together, these training aspects are designed to provide students with the scientific knowledge and collaborative prowess to work together in an interdisciplinary team to address the most compelling and intractable scientific questions, with the goal of developing the next generation of biomedical researchers. “Value-added” features of the UTSW CBI training program include: (a) an advanced course in Drug Discovery taught by experts in academia and industry; (b) an improved Enzymes and Disease course that facilities interdisciplinary and collaborative science through peer-led team learning; (c) personalized instruction in scientific writing, specifically aimed at funding opportunities; (d) training in scientific communication through coached production of ScienceSketch YouTube videos; (e) trainee-designed participation in mini-sabbaticals to enhance cross-disciplinary and non-academic training; (f) monthly meetings between CBI trainees and faculty advisory committee that offer collegial support and career enrichment opportunities; and (g) support for teaching and outreach activities.