MonitoRing the Effect of TRAnscutaneous neuro-electrical muscular stImulation of the common peroneal Nerve using the geko device on cerebral haemodynamics in patients with ischaemic strokes: RETRAIN

中风是英国每年的第三大杀手。每年有超过113，000人中风，其中32，000人将在一年内死亡。每年中风给国家造成的损失超过240亿英镑。这是由35亿英镑的NHS成本组成的，50亿英镑的社会服务成本和160亿英镑的家庭和朋友等非正式护理人员的成本。这些成本将在未来15年内翻一番。该项目旨在展示创新设备的能力（Geko设备）通过增加脑血流量来改善中风患者的恢复，同时防止中风患者的DVT。研究表明，geko设备可以防止深静脉血栓。静脉血栓形成（DVT），它已被授权用于在NHS，以防止DVT的发生。这将节省NHS的成本约£17万，每年提高中风幸存者的生活质量。该公司目前销售的geko设备在世界各地。这是一个小型电池供电的设备，贴在膝盖后面，向神经发送非常小的电信号。然而，最近的一些研究--在健康志愿者身上使用geko设备--表明，除了增加腿部的血流量外，该设备还能增加大脑中的血流量和氧气水平。增加中风患者的这两样东西可能是提高他们康复机会的一个极其重要的工具，他们恢复得有多好。为了了解geko设备在这方面的表现如何，我们想在严重的中风患者身上重复这项工作。首先，我们需要找到geko设备的设置，使血液在大脑中流动最好。其次，我们需要对现有的病人护理方式进行测试，看看geko设备是否是一种改进。为此，我们与发明了geko设备第一类;以及英国治疗严重中风患者最好的医院之一;切斯特伯爵夫人。一旦该设备被证明安全有效，它将出售给世界各地的医疗机构。为此，该项目正在与世界上最大的中风设备公司之一建立伙伴关系。

Stroke is the third biggest killer in the UK every year. Over 113,000 people suffer a stroke every year, of these, 32,000 will die within a year.Each year strokes cost the country over £24 billion. This is made up of £3½ billion of NHS costs, £5 billion of Social Services costs and £16 billion in costs of informal carers such as family and friends.These costs are set to double over the next 15 years.This project intends to demonstrate the ability of an innovative device (the geko device) to improve recovery from stroke by increasing blood flow to the brain while preventing DVT in stroke patients.Research has shown the geko device prevents deep vein thrombosis (DVT) and it has been authorised for use in the NHS to prevent DVTs happening.This will save the NHS costs of about £17 million every year and improve the quality of life of stroke survivors.The company currently sells the geko device around the world. It is a small battery-powered device that sticks to the back of the knee where it sends very small electrical signals to a nerve. This, then, causes the muscles in the calf to contract causing blood to move around the body.However, some recent research - using the geko device on healthy volunteers - has shown that, as well as increasing blood flow in the leg, the device also increases blood flow and oxygen levels in the brain.Increasing these two things in stroke patients could be an extremely important tool in improving their chances of recovery and how well they recover.To find out how well the geko device performs in doing this, we want to repeat this work in serious stroke patients.Firstly, we need to find the geko device settings that make blood flow best in the brain.Secondly, we need to test the device against existing ways that patients are cared for to see if the geko device is an improvement.To do this we have formed a partnership between the company that invented the geko device: Firstkind; and one of the best hospitals in the country for treating serious stroke patients; The Countess of Chester.Once the device is proven safe and effective, it will be sold to healthcare organisations around the world. To do this, the project is developing a partnership with one of the world's biggest stroke-equipment companies.