UCSF Career Development Program in Cardiopulmonary, Hematologic, and Immunologic Comorbidities of HIV (CHIC)

项目摘要/摘要 我们建议在心肺领域建立一个创新的、跨学科的K12职业发展计划， 加州大学旧金山分校的HIV血液学和免疫学共病(CHIC) (加州大学旧金山分校)该计划的主要重点将是艾滋病毒相关的临床和翻译(C&T)研究 心肺疾病在美国和国际上都有，但项目教员拥有内容专业知识 容纳对艾滋病毒相关血液病的C&T研究感兴趣的有价值的学者和 艾滋病治愈研究。这项K12计划将培养致力于职业生涯的杰出的医学博士、医学博士和博士学者 在C&T研究方面，利用大量的学术培训、职业发展和研究资源 加州大学旧金山分校包括加州大学旧金山分校临床与翻译科学研究所(CTSI)、加州大学洛杉矶分校艾滋病研究所 加州大学洛杉矶分校格拉德斯通艾滋病研究中心(CFAR)、加州大学旧金山分校心血管研究所 (CVRI)和血液系统研究所(BSRI)。这款K12将汇集35个已完成的， 在单一计划下的经验丰富的专家教员研究人员，将加强现有的研究 合作和催化新的合作。项目教员主要来自以下3个部门：肺科 和重症监护医学；心脏病学；艾滋病毒、传染病和全球医学 医学院的医学系。教职员工已经证明了独立研究的记录 资金、成功的研究合作和同行评议的出版物。与加州大学旧金山分校的丰富保持一致 合作的传统，K12教职员工与现有的研究合作和共同撰写的出版物 其他项目教员，为学者提供一个庞大的导师和共同导师网络。项目教职员工有 旧金山和国际上丰富的艾滋病毒临床队列将成为 指导K12学者的C&T研究经验。K12的教职员工都是经验丰富且成功的导师。 教师也是加州大学旧金山分校CTSI临床研究硕士(MAS)项目和KL2 K学者项目的负责人 该计划将为K12学者提供大部分关于C&T研究方法的正式教学培训。 最后，K12教员也是K12项目的项目主任，在肺病的Omics和实施 加州大学旧金山分校心肺疾病研究，肺病T32培训基金项目主任， 心血管疾病和艾滋病毒翻译研究，以及心脏病、艾滋病毒、感染性心脏病科长 以及全球医学和实验医学部门，提供无与伦比的领导， 在学术培训和职业发展方面的经验和专业知识，以及获得深入和 补充一批才华横溢的学者。我们的主要目标是生产下一代 研究艾滋病毒相关的心脏、肺和血液疾病的研究人员。

PROJECT SUMMARY/ABSTRACT We propose to establish an innovative, interdisciplinary K12 Career Development Program in Cardiopulmonary, Hematologic, and Immunologic Comorbidities of HIV (CHIC) at the University of California San Francisco (UCSF). The primary focus of this program will be clinical and translational (C&T) research in HIV-associated cardiopulmonary diseases both in the US and internationally but program faculty possess the content expertise to accommodate meritorious scholars interested in C&T research in HIV-associated hematologic diseases and HIV cure research. This K12 program will train exceptional MD, MD/PhD, and PhD scholars dedicated to careers in C&T research, leveraging the substantial academic training, career development, and research resources of UCSF including the UCSF Clinical & Translational Science Institute (CTSI), the UCSF AIDS Research Institute (ARI), the UCSF-Gladstone Center for AIDS Research (CFAR), the UCSF Cardiovascular Research Institute (CVRI), and the Blood Systems Research Institute (BSRI). This K12 will bring together 35 accomplished, experienced, and expert faculty researchers under a single program that will strengthen existing research collaborations and catalyze new ones. Program faculty are primarily from the following 3 Divisions: Pulmonary and Critical Care Medicine; Cardiology; and HIV, Infectious Diseases, and Global Medicine within the Department of Medicine in the School of Medicine. Faculty have demonstrated records of independent research funding, successful research collaborations, and peer-reviewed publications. In keeping with UCSF's rich tradition of collaboration, K12 faculty have existing research collaborations and co-authored publications with other program faculty, providing scholars with a vast network of mentors and co-mentors. Program faculty have a wealth of HIV clinical cohorts both in San Francisco and internationally that will serve as the foundation for the mentored C&T research experience of K12 scholars. K12 faculty are experienced and successful mentors. Faculty are also leaders of the UCSF CTSI Masters in Clinical Research (MAS) Program and KL2 K Scholars Program that will provide much of the formal didactic training in C&T research methods for the K12 scholars. Finally, K12 faculty are also Program Directors of K12 Programs in Omics of Lung Disease and Implementation Research in Heart and Lung Diseases at UCSF, Program Directors of T32 Training Grants in Lung Disease, Cardiovascular Disease, and HIV Translational Research, and Division Chiefs of Cardiology, HIV, Infectious Diseases, and Global Medicine and Experimental Medicine Divisions, providing unparalleled leadership, experience and expertise in academic training and career development as well as access to a deep and replenishing pool of exceptionally-talented scholars. Our main goal is to produce the `next generation' of researchers in HIV-associated heart, lung and blood diseases.