Viral Oncology Training Grant

项目总结/摘要 要求继续支持杜克大学医学部的病毒肿瘤学培训计划 中心该计划自1975年以来一直得到资助，这是第七届任期的延期请求。 程序.申请资助3名博士前学员和5名博士后学员。的 参与的教师包括杜克大学医学中心的21名成员，其中许多人有小学或 分子遗传学和微生物学系的二级任命。额外参与 教师有任命在内科，儿科，神经外科，外科，药理学部门 和癌症生物学或人口健康科学。参与教师的研究兴趣范围 从病毒复制和病毒/宿主相互作用的基础分子遗传学研究，到病毒和 细胞癌基因的作用，人类免疫缺陷病毒的免疫学和分子病毒学， 癌症易感病毒和病毒在治疗人类恶性肿瘤方法中的用途。的 研究计划已被证明是一个有效的培训基础，为博士前和博士后学员。 博士预科课程包括四个学期的学术工作，然后进行初步考试。后 成功完成这些要求，全职研究占据了培训计划的其余部分。 博士后培训计划的重点是参与实验室的全职研究。两者 博士前和博士后计划是由部门和计划研讨会系列的各种增强 类型以及病毒学杂志俱乐部，每月为参与实验室举行工作进展会议， 两个年度minisymoposis，一个在秋季的“病毒肿瘤学和艾滋病病毒”，一个在春季， “人类致病病毒“这些活动促进了项目成员之间的沟通， 其他学生和教师在杜克，最终的利益不仅是学员，但整个机构。 我们亦为学员提供丰富的职业及专业发展培训及机会。 这些包括培训拨款写作，科学演示，职业指导，由专门的教师咨询 委员会和外部咨询委员会，并与VOTG校友网络整合，现在超过200 在整个生物医学研究领域都很强大。

PROJECT SUMMARY/ABSTRACT Continued support is requested for a training program in Viral Oncology at Duke University Medical Center. The program has been funded since 1975 and this is a request for renewal for the seventh term of the program. Funds are requested for the support of 3 predoctoral trainees and 5 postdoctoral trainees. The participating faculty consists of 21 members of Duke University Medical Center, many of whom have primary or secondary appointments in the Department of Molecular Genetics and Microbiology. The additional participating faculty have appointments in the Departments of Medicine, Pediatrics, Neurosurgery, Surgery, Pharmacology and Cancer Biology, or Population Health Sciences. The research interests of the participating faculty range from basic molecular genetic studies of virus replication and virus/host interactions, to the study of viral and cellular oncogene action, the immunology and molecular virology of the human immunodeficiency virus as a cancer-predisposing virus and the use of viruses in approaches to the treatment of human malignancies. The research program has proven to be an effective training basis for both predoctoral and postdoctoral trainees. The predoctoral program involves four semesters of academic work followed by a preliminary examination. Upon successful completion of these requirements, full time research occupies the remainder of the training program. The postdoctoral training program is focused on full time research in the participating laboratories. Both the predoctoral and the postdoctoral program are enhanced by departmental and program seminar series of various types as well as a virology journal club, monthly works in progress meetings for participating laboratories and two annual minisymposia, one in the fall on “Viral Oncology and AIDS Malignancy” and one in the spring on “Pathogenic Human Viruses." These activities foster communication between members of the program, and with other students and faculty at Duke, to the ultimate benefit of not only the trainees but the institution in general. Trainees are also provided with a wealth of career and professional development training and opportunities. These include training in grant writing, scientific presentation, career mentoring by dedicated faculty advising committees and an external advisory committee, and integration with a network of VOTG alumni now over 200 strong across the landscape of the biomedical research enterprise.