Preventing Alcohol and Other Drug Use and Violence among Latino Youth

预防拉丁美洲青年的酒精和其他药物使用和暴力 项目总结/摘要 这个K 01研究和培训奖推进了我的长期目标，即开发旨在针对 酒精和其他药物（AOD）的使用和暴力在拉丁美洲青少年在美国。青少年AOD 使用和暴力之间存在着深刻的相互关系，因为有证据清楚地表明，青少年使用者 有可能实施暴力，急性中毒和慢性使用都与攻击有关。此外，委员会认为， 前瞻性研究的结果表明，青年参与暴力也预示着随后使用爆炸物驱替剂。 拉丁裔早期青少年（11至14岁）在饮酒和参加暴力活动方面存在危险。 行为然而，仍然迫切需要开发易于扩展的预防性干预措施， 针对拉丁裔青年使用AOD和暴力的措施。拟议的研究计划侧重于适应 一个得到政府支持的AOD使用干预（keepin' it真实的[kiR]），包括对暴力的关注，反过来， 测试经调整的预防性干预措施，以检查其可行性、可接受性和初步效果。的 拟议的多学科培训计划旨在帮助我发展必要的技能， 作为独立的研究人员，进行高影响力的翻译研究。具体而言，这将 包括使用定性方法的培训，为适应和制定干预措施提供信息， 系统地调整/制定干预措施的过程，最后，测试干预措施和预防措施， 成果研究。我的培训计划与这三个学习目标直接相关。在目标1中，我将进行聚焦 小组访谈，目的是为修改《儿童权利公约》提供信息，使其包括对预防暴力的关注。在目标2中，我 我将在这一形成性研究的基础上，通过调整kiR，将重点放在青年暴力和暴力 预防在目标3中，我将领导一项试点随机对照试验（RCT）， 为了评估适应性干预的可行性/可接受性，并评估信号是否 的有效性是目前的AOD使用和暴力的结果。预计拟议研究的贡献 开发一种易于扩展的、多成分的预防性干预措施，以防止AOD的使用和暴力 在拉丁裔早期青少年中，可以在一个完全有效的RCT（R 01）中进行测试。这项研究提出了一个重要的- 在一个庞大而迅速增长的少数群体中，预防科学存在着重大差距， 相关的健康差异。此外，K 01指导研究科学家发展奖将为我提供 有了培训，研究经验，和必要的初步数据，使飞跃到独立的投资， 鳄鱼状态这样的经验和培训是我努力建立在我以前的研究基础上的基础， 这可以转化为旨在产生现实世界效益的干预研究项目。

Preventing Alcohol and Other Drug Use and Violence among Latino Youth Project Summary/Abstract This K01 research and training award advances my long-term goal of developing interventions designed to target alcohol and other drug (AOD) use and violence among Latino adolescents in the United States. Adolescent AOD use and violence are profoundly interrelated as evidence clearly indicates that adolescent AOD users are more likely to enact violence and that both acute intoxication and chronic use are related to aggression. Moreover, results from prospective studies suggest that youth involvement in violence also predicts subsequent AOD use. Latino early adolescents (ages 11 to 14) are disproportionally at risk to use alcohol and take part in violent behavior. And yet, there remains a critical need for the development of readily-scalable, preventative interven- tions that target AOD use and violence among Latino youth. The proposed research plan focuses on adapting an empirically-supported AOD use intervention (keepin' it REAL [kiR]) to include a focus on violence and, in turn, testing the adapted preventative intervention to examine its feasibility, acceptability, and preliminary effects. The proposed multidisciplinary training plan is designed to assist me in developing the necessary skills to effectively function as an independent researcher and carry out high-impact translational research. Specifically, this will include training in the use of qualitative methods to inform the adaptation and development of interventions, the process of systematically adapting/developing interventions, and, finally, the testing of interventions and preven- tion outcomes research. My training plan is directly linked to the three study aims. In Aim 1, I will conduct focus group interviews designed to inform the adaptation of kiR to include a focus on violence prevention. In Aim 2, I will build upon this formative research by adapting kiR to incorporate a focus on youth violence and violence prevention. And, in Aim 3, I will lead a pilot randomized controlled trial (RCT) in which the adapted intervention is tested in order to assess the feasibility/acceptability of the adapted intervention and assess whether a signal of efficacy is present for AOD use and violence outcomes. The contribution of the proposed research is expected to be the development of a readily-scalable, multicomponent preventative intervention for AOD use and violence among Latino early adolescents that can be tested in a fully-powered RCT (R01). This study addresses a signif- icant gap in prevention science among a large and rapidly-growing minority group experiencing multiple, inter- related health disparities. Moreover, this K01 Mentored Research Scientist Development Award will provide me with the training, research experience, and preliminary data necessary to make the leap to independent investi- gator status. Such experience and training is foundational in my effort to build upon my prior research in ways that can translate into intervention research projects designed to yield real-world benefits.