Molecular Biophysics Training Program at Stanford

摘要 斯坦福生物物理学项目的使命是培养学生具有强大的、跨学科的、 有意义的生物学问题的定量方法，同时建立一种严格的氛围 包容性、多样性以及高研究品行和道德。为了实现这些目标，受训人员参加了 课程作业、有指导的初级研究和其他旨在加强培训的活动；这些 作为STEM劳动力的一部分，毕业生为下一步的职业生涯做好了准备。该计划 需要物理和生物科学的研究生水平的课程，参加系列研讨会和 退而求其次，发展高水平的自主研究能力。这方面的教职员工 来自人文学院21个系的跨部门博士前培训计划 科学、医学、工程和斯坦福同步辐射实验室。学生培训和 研究中心是物理化学原理和方法在生物学问题上的应用，如 以及新方法的发展。分子性质与分子间的定量关系 更高水平的细胞/组织属性是该计划日益关注的重点，量化的新兴领域也是如此 细胞和器官生物学。总体而言，这个培训计划充分利用了学生的背景和对 同时培养跨越生物尺度的创造性、协作性、高技能的方法。 实习生在被斯坦福大学录取时被任命，为期最长2年；所要求的12个职位将产生 通过大学和外部资助的奖学金，班级规模为8-10人。该校目前有59名学生 计划(18.6%的URM)，大多数具有物理科学、生物化学或 工程学。重要的是，我们最近的努力导致了学生背景的多样化 与少数群体服务机构(加州大学默塞德分校)合作的生物物理学计划和夏季研究 面向斯坦福大学招收URM学生的项目。为了最大限度地留住学员，第一年由 项目主任和与每个学生的论文委员会的年度会议确保了一个平衡的学术 课程是为每个学生的背景量身定做的，并且可接受的表现水平是 维护好了。与顾问进行必要的IDP会议，以确保职业发展和RCR/R&R指导； 后者也通过必修课程提供，包括统计课程和各种选修课 供品。学生积极参与计划活动，建立一个有凝聚力的社区；计划 受益于高水平的大学支持和参与。开展的基础研究和应用研究 我们的受训人员为开发针对特定分子的药物奠定了基础，以了解 环境刺激与细胞和组织行为的关系及开发新方法 用于检测和治疗包括癌症和神经病理学在内的疾病。

Abstract The mission of the Stanford Biophysics Program is to develop students with strong, interdisciplinary, quantitative approaches to meaningful biological problems, while establishing a rigorous atmosphere of inclusion, diversity, and high research conduct and ethics. To meet these goals, trainees participate in coursework, mentored primary research, and other activities designed to enhance their training; together these opportunities prepare graduates for the next step in their careers as part of the STEM workforce. The Program requires graduate-level coursework in physical and biological sciences, participation in seminar series and the retreat, and the development of a high level of proficiency in independent research. Faculty in this interdepartmental predoctoral training program come from 21 departments in the Schools of Humanities and Sciences, Medicine, Engineering, and the Stanford Synchrotron Radiation Laboratory. Student training and research centers on the application of physical and chemical principles and methods to biological problems, as well as the development of new methods. The quantitative relationship between molecular properties and higher-level cell/tissue properties is an increasing focus of the Program, as are emerging areas of quantitative cell and organ biology. Overall, this training program capitalizes on student backgrounds and interests in the physical sciences while fostering creative, collaborative, highly skilled approaches that span biological scales. Trainees are appointed upon admission to Stanford for up to 2 years; the 12 requested slots will generate class sizes of 8-10 through university and externally funded fellowships. There are currently 59 students in the Program (18.6% URMs), most with undergraduate backgrounds in physical science, biochemistry, or engineering. Importantly, our recent efforts have led to diversification of the backgrounds of students in the Biophysics Program through partnerships with a minority-serving institution (UC Merced) and summer research programs that recruit URM students to Stanford. To maximize trainee retention, first-year advising by the Program Director and annual meetings with each student’s thesis committee ensure that a balanced academic program is tailored to the background of each student and that an acceptable level of performance is maintained. Required IDP meetings with the advisor ensure career development and RCR/R&R instruction; the latter is also provided through required coursework including a Statistics class and a variety of elective offerings. Students are heavily involved in program activities, establishing a cohesive community; the Program benefits from high levels of University support and engagement. The fundamental and applied research carried out by our trainees is the cornerstone for developing drugs targeted to specific molecules, for understanding the relationships between environmental stimuli and cell and tissue behavior, and for developing new methods for detecting and treating diseases including cancer and neurological pathlogies.