Biological Data Acquisition and Analysis Core

生物数据采集和分析核心的目标如下：1)加强 现有中心研究和先导研究的生物资源；2)利用现有资源最大限度地提高生产力 生物资源；3)通知、教育和培训中心调查人员、附属机构、博士后研究员以及 学生学习新的和创新的生物学方法；以及4)促进跨中心的协作科学 项目。核心工作人员将与中心项目提供个性化咨询，以评估资源和 机会，制定计划以加强资源和启动协作，提供项目管理 支持确保与设施的顺利协调并及时完成，补充项目资源以 协助数据分析和撰写，并为调查人员提供培训/教育机会 和员工。该团队将由蒂莫西·斯图尔特兰博士共同领导，他在使用大脑成像方面拥有专业知识 技术来研究与自我调节相关的机制，以及药理学家辛西亚·库恩博士，他的 实验室将为寻求分析压力和免疫相关生物标记物的研究提供核心设施。他们的 团队将加入一系列在基因组学/表观遗传学、神经成像、生物标记物方面的合作机构/资源 评估、电子健康记录、生物信息学和生物库。将这些资源与中心匹配 项目将激发人们对早期经验、监管流程、 潜在的生物系统和行为结果。

The objectives of the Biological Data Acquisition and Analysis Core are the following: 1) to enhance the biological resources of existing Center studies and pilot studies; 2) to maximize their productivity with existing biological resources; 3) to inform, educate and train Center investigators, affiliates, postdoctoral fellows, and students on novel and innovative biological methods; and 4) to promote collaborative science across Center projects. The core staff will provide individualized consultation with Center projects to evaluate resources and opportunities, develop a plan to enhance resources and initiate collaboration, provide project management support to ensure smooth coordination with facilities and timely completion, supplement project resources to assist with data analysis and writing, and provide access to training/educative opportunities to investigators and staff. The team will be co-led by Dr. Timothy Strauman, who has expertise in the use of brain imaging techniques to study mechanisms relevant for self-regulation, and Dr. Cynthia Kuhn, a pharmacologist, whose laboratory will provide a core facility for studies looking to assay stress and immune-related biomarkers. Their team will be joined by a set of partner facilities/resources in genomics/epigenetics, neuroimaging, biomarker assessment, electronic health records, bioinformatics and biobanking. Matching these resources with Center projects will stimulate novel insights into the interplay between early experiences, regulatory processes, underlying biological systems, and behavioral outcomes.