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中文摘要
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项目总结/摘要 此更新申请寻求NICHD支持5第一年和5第二年的职位, 儿科科学家发展计划(PSDP),儿科研究员的职业发展途径 自1987年以来,已有192名医学科学家毕业。该计划的目标仍然是 自成立以来一直保持不变:(a)招募儿科研究员,他们具有杰出的潜力, 成功的调查职业生涯可以在一个密集的指导环境中发展,(B)扩大 训练有素的儿科医生科学家的管道,谁将催化尖端的发现 在儿童健康方面的贡献,并领导未来的儿科部门。 私营部门发展方案的独特之处包括在北美征聘研究员和导师, 它在研究金期间对职业发展的高度重视, 在医学院儿科系主任协会(AMSPDC)的支持下, 关于儿科系外的研究环境,及其指导方法, 包括研究导师、PSDP咨询委员会和儿科系主任。 咨询委员会包括一个指导委员会,负责制定方案政策; 委员会面试PSDP候选人;和一个独立的方案评估委员会 衡量该计划在确保研究员成功方面的有效性。PSDP的核心是 每年的职业发展课程,召集PSDP研究员,咨询委员会,和所有美国 和加拿大儿科系主任在AMSPDC会议。PSDP毕业生曾担任 335个NIH RPG的PI,其中53%目前正在使用。基于NIH RPG的总奖励, PSDP毕业生是PI,NICHD投资回报率为8.8倍。 2017-2021年的创新包括a)通过纳入部门支持来利用NICHD资金 最多5名三年级研究员,他们将被任命为导师,75-80%的研究时间受到保护 和B)扩大我们的职业发展课程与成人学习教育模块, 强调研究员到教师的过渡和团队科学,在AMSPDC现场和通过 基于网络的案例研究。私营部门发展计划实施了一项全面战略, 儿童健康研究的界限,发展经过严格培训的儿科医生的研究事业, 医生科学家,并产生下一代的儿科研究领导者。
英文摘要
PROJECT SUMMARY/ABSTRACT This renewal application seeks NICHD support for 5 first-year and 5 second-year positions in the Pediatric Scientist Development Program (PSDP), a career development pathway for pediatric fellows from which 192 physician-scientists have graduated since 1987. The objectives of the program remain unchanged since its inception: (a) to recruit pediatric fellows whose outstanding potential for a successful investigative career can be developed in an intensively mentored setting and (b) to expand the pipeline of superbly trained pediatric physician-scientists, who will catalyze cutting-edge discoveries in child health and lead the pediatric departments of the future. Unique aspects of the PSDP include its North American scope for recruitment of fellows and mentors, its intensive focus on career development during fellowship, its supra-institutional governance under the aegis of the Association of Medical School Pediatric Department Chairs (AMSPDC), its emphasis on research environments outside departments of pediatrics, and its approach to mentoring that encompasses research mentors, PSDP advisory committees, and pediatric department chairs. Advisory Committees include a Steering Committee, which sets programmatic policy; a Selection Committee to interview PSDP candidates; and an independent Program Evaluation Committee measures the program’s effectiveness in ensuring fellows’ success. A centerpiece of the PSDP is the annual career development curriculum that convenes PSDP fellows, advisory committees, and all US and Canadian pediatric department chairs at the AMSPDC meeting. PSDP graduates have served as PIs on 335 NIH RPGs, of which 53% are currently active. Based on total awards of NIH RPGs with PSDP graduates are PIs, the return on NICHD investment is 8.8 fold. Innovations for 2017-2021 include a) leveraging NICHD funding by incorporating departmental support for up to 5 third-year fellows who will be appointed as instructors with 75-80% protected research time and b) expanding our career development curriculum with adult-learning educational modules that emphasize the fellow-to-faculty transition and team science, presented on site at AMSPDC and through web-based case-based studies. The PSDP has implemented a comprehensive strategy to expand the boundaries of child health research, to develop the research careers of rigorously trained pediatric physician-scientists, and to produce the next generation of investigative leaders in pediatrics.
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Identifying and modeling immune correlates of protection against congenital CMV transmission after primary maternal infection
Pediatric Scientist Development Program
Escape of maternal plasma broadly neutralizing antibody as a mechanism of mother to child HIV transmission
Pediatric Scientist Development Program
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