Mentoring Translational Cancer Research in Oklahoma

摘要-整体组件 该提案的总体目标是提高癌症研究的质量和数量， 俄克拉荷马州的俄克拉荷马州大学健康科学中心（OUHSC）的NIH资助， 有前途的初级目标调查员（目标调查员），并发展对基础设施的支持， 癌症研究。在COBRE第一阶段成功的基础上，COBRE第二阶段赠款将支持 并维持在上一个第一阶段资助期间开发的基础设施， 新的目标初级调查员队伍这个COBRE将继续加强癌症研究的进程 在俄克拉荷马州，并加强癌症中心的研究基础，基础设施和核心能力。的 该COBRE的重点突出、结构合理的指导过程将对帮助TJIs产生决定性影响 实现国家自主融资。最后，正如COBRE第一阶段所观察到的那样， II赠款将加速癌症中心的发展，因为它正在向提交一个有竞争力的 NCI癌症中心支持补助金申请。COBRE的首要目标是增强癌症 俄克拉荷马州的研究能力将通过以下具体目标来实现：1）维持 成功指导癌症研究中有前途的初级目标初级研究人员，使他们能够成为 独立的NIH资助的研究人员; 2）支持和加强建立的研究基础设施 在COBRE的第一阶段;以及3）促进和加强多学科合作研究， 促进翻译研究。

Abstract – Overall Component The overall objectives of the proposal are to improve the quality and quantity of cancer research and increase NIH funding at the University of Oklahoma Health Sciences Center (OUHSC), Oklahoma through the mentoring of promising junior Target investigators (Target investigators) and to develop support for the infrastructure for cancer research. Building on the success of the Phase I of this COBRE, the Phase II COBRE grant will support and sustain the infrastructure developed during the previous Phase I funding period in addition to mentoring a new cadre of target junior investigators. This COBRE will continue the process of strengthening cancer research in Oklahoma and enhance the research base, infrastructure, and core capacities of the Cancer Center. The focused and structured mentoring process of this COBRE will have a determinative influence helping TJIs achieve independent national funding. Finally, as has been observed with the Phase I of this COBRE, the Phase II grant will accelerate the development of the Cancer Center as it progresses towards submitting a competitive NCI Cancer Center Support Grant application. The overarching objective of the COBRE in enhancing the cancer research capacity of Oklahoma will be accomplished through the following specific aims: 1) To sustain the successful mentoring of promising junior target junior investigators in cancer research, enabling them to become independent NIH-funded investigators; 2) To support and strengthen the research infrastructure established during the Phase I of this COBRE; and 3) To foster and enhance multidisciplinary collaborative research to facilitate translational research.