Mentoring Translational Cancer Research in Oklahoma

指导俄克拉荷马州的转化癌症研究

• 批准号: 8216750
• 负责人: Danny N. Dhanasekaran
• 金额: $ 211.04万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-05 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8216750
• 关键词: Address; Affect; Area; Basic Science; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Patient; Cancer Research Infrastructure; Cancer Research Project; Centers for Disease Control and Prevention (U.S.); Centers of Research Excellence; Cessation of life; Clinical; Clinical Research; Collaborations; Commit; Communities; Comprehensive Cancer Center; Data; Dental; Development; Diabetes Mellitus; Diagnosis; Disease; Economic Burden; Education; Environment; Fostering; Foundations; Funding; Generations; Gifts; Goals; Grant; Health; Health Sciences; Incidence; Interdisciplinary Study; Investments; Leadership; Life; Malignant Neoplasms; Mentors; NCI Center for Cancer Research; Names; National Cancer Institute; Oklahoma; Pathogenesis; Pharmacy facility; Pilot Projects; Population; Positioning Attribute; Prevalence; Prevention; Prevention program; Public Health; Research; Research Infrastructure; Research Personnel; Resistance; Resources; Rural; Science; Scientist; Strategic Planning; Structure; Time; Training; Translational Research; Tumor Biology; United States National Institutes of Health; Universities; Vision; Work; anticancer research; base; cancer care; cancer research center director; cancer therapy; college; design; disorder prevention; experience; fight against; health disparity; improved; interdisciplinary approach; microbial; mortality; named group; novel; novel diagnostics; programs; public health relevance; ranpirnase; social; statistics

DESCRIPTION (provided by applicant): The overall objectives of is to Improve the quality and quantity of cancer research at the University of Oklahoma Hearth Sciences Center (OUHSC), to increase NIH funding in Oklahoma through the mentoring of promising junior investigators (PJIs) and to develop support for the infrastructure for cancer research, this COBRE grant will greatly strengthen cancer research in Oklahoma and enhance the research base, infrastructure, and core capacities of the Cancer Center. The focused and structured mentoring experience that the COBRE grant supports will be a determinative influence helping PJIs achieve independent national funding. Finally, as has been seen on campus in the areas of Vision, Diabetes, Dental Sciences and Microbial Pathogenesis, the CoBRE grant will help accelerate the development of the Cancer Center as it progresses towards a submitting a competitive NCI Cancer Center Support Grant application. The Specific Aims of this CBRE application are: 1. To mentor promising junior investigators (PJIs) In cancer research, enabling them to become independent NIH-funded investigators. Four PJIs have been selected. Each has been assigned a mentor and a co-mentor who are established cancer researchers in Oklahoma with expertise related to the PJI's project. The four PJIs have diverse but related projects that are integrated under the overall theme of "Tumor Biology: Resistance to Cancer Therapy and Mitigating Strategies." 2. To establish and develop research infrastructure to support cancer research, optimize the research environment for the PJIs, and form a core resource for the developing Stephenson Oklahoma Cancer Center. Four shared Cores will be established in this COBRE to assist the PJI projects and to serve the cancer research community in Oklahoma. 3. To foster and enhance collaborations between basic scientists and clinicians, and to facilitate translational research directed toward the development of new diagnostics and treatments for cancer.

描述（由申请人提供）：总体目标是提高俄克拉何马大学灶台科学中心（OUHSC）癌症研究的质量和数量，通过有前途的初级研究人员（PJIs）的指导增加俄克拉何马州的NIH资金，并为癌症研究的基础设施提供支持，这项COBRE赠款将大大加强俄克拉何马州的癌症研究，增强癌症中心的研究基地、基础设施和核心能力。COBRE赠款所支持的重点突出和有组织的指导经验将成为帮助pji获得独立国家资助的决定性影响。最后，正如在视力、糖尿病、牙科科学和微生物发病机制等领域所看到的那样，CoBRE的资助将有助于加快癌症中心的发展，因为它正朝着提交有竞争力的NCI癌症中心支持资助申请的方向发展。世邦魏理仕申请的具体目标是：1。指导有前途的初级研究人员（PJIs）在癌症研究中，使他们成为独立的nih资助的研究人员。四个pji已被选中。每个人都被分配了一名导师和一名共同导师，他们是俄克拉何马州的知名癌症研究人员，具有与PJI项目相关的专业知识。这四个pji有不同但相关的项目，这些项目被整合在“肿瘤生物学：对癌症治疗的耐药性和缓解策略”的总体主题下。2. 建立和发展支持癌症研究的研究基础设施，优化pji的研究环境，并为发展中的斯蒂芬森俄克拉何马州癌症中心形成核心资源。该COBRE将建立四个共享核心，以协助PJI项目并服务于俄克拉荷马州的癌症研究界。促进和加强基础科学家和临床医生之间的合作，促进针对癌症新诊断和治疗方法的转化研究。