Cognitive Load Measurement during Neuromyoelectric Prosthesis Use with Sensory Feedback and Intuitive Motor Control

项目摘要 拟议工作的主要目标是确定感觉反馈和扩展使用 减少控制先进灵巧和感应化假肢的认知负荷。假肢 上肢截肢者的技术正在迅速发展。身体上的改善包括两个方面 组件：机械臂和神经肌肉接口。尽管创新前景看好 在假肢功能方面，上肢假肢的弃置率高(高达50%)。科学的 社区正在开发先进的控制范例，提供更直观的控制并使用触觉传感器 以恢复触觉。这些进步有可能提高满意率并降低 遗弃率；然而，当前的指标没有考虑用户努力，这是确定 可行的产品。假肢系统的改进，无论是通过更直观的控制范例还是通过感觉 反馈通常通过任务的表现来量化，这些任务可能代表或可能不代表典型的日常生活 活动。虽然这些指标很有用，但它们不一定反映最终用户的偏好。 尽管特定的系统可以实现精细控制，但实现这种控制所需的努力可能是 禁止常规使用，导致不可行的产品。因此，结合努力措施，在此 被描述为认知负荷，可以更完整地告知假体系统所需的特征。 这项建议的主要目的是测量假体使用过程中的认知负荷。我们建议 调整在其他领域(例如，驾驶研究)中使用的认知负荷测量，以适应我们的高级研究 神经肌电假体。我们的第一个目标是开发一种健壮的方法来测量认知负荷 生理、行为和受试者测量，包括斜视测量、心电图和 脑电图仪(目标1)。目标1将揭示特定认知负荷的优势和局限性 假体研究中的措施。然后，我们将应用这些方法来确定感觉反馈是否可以减少 假体使用过程中的认知负荷(目标2)。目标2阐明感觉反馈在假肢中的作用 使用，一种在场上的电流推力。最后，我们将确定延长期间(六个月)认知负荷是否降低 在家中使用先进的神经肌电假体(目标3)。目标3将提供对 在家庭环境中长期使用先进假体的认知影响。 这些目标的成功将建立一条从根本上不同但又至关重要的途径来评估 以患者为中心的假体改进的可行性。记录的感觉反馈的有效性 在假肢控制中的长期使用不仅具有科学价值，而且也是翻译这些 先进的假体技术被临床接受和使用。总而言之，该项目将提供 可用于上肢假肢社区及其他领域的方法学。

Project Summary The primary goal of the proposed work is to determine whether sensory feedback and extended use reduce the cognitive load for controlling an advanced dexterous and sensorized prosthetic limb. Prosthetic technologies for upper-limb amputees are advancing rapidly. The physical improvements involve two components: the robotic limb and the neuromuscular interface. Despite innovations promising increased prosthetic function, high abandonment rates (up to 50%) are seen with upper-limb prostheses. The scientific community is developing advanced control paradigms providing more intuitive control and using haptic sensors to restore the sense of touch. These advancements have the potential to improve satisfaction rates and reduce abandonment rates; however, current metrics do not consider user effort, which is necessary in determining a viable product. Improvements to prosthetic systems, whether through more intuitive control paradigms or sensory feedback are typically quantified through performance in tasks that may or may not represent typical daily activities. Although these metrics are useful, they do not necessarily reflect the preferences of the end-user. Although a particular system may enable fine control, the effort required to achieve such control may be prohibitive to routine use, resulting in a nonviable product. Thus, incorporating measures of effort, herein described as cognitive load, can more completely inform the desirable characteristics of a prosthetic system. The main objective of this proposal is to measure cognitive load during prosthesis use. We propose to adapt cognitive load measures used in other fields (e.g., driving research) to our research with advanced neuromyoelectric prostheses. Our first aim is to develop a robust method for measuring cognitive load through physiological, behavioral, and subject measures, including pupillometry, electrocardiography, and electroencephalography (Aim 1). Aim 1 will expose the advantages and limitations of specific cognitive load measures in prosthetic research. We will then apply these methods to determine if sensory feedback can reduce cognitive load during prosthetic use (Aim 2). Aim 2 elucidates the usefulness of sensory feedback in prosthesis use, a current thrust in the field. Lastly, we will determine if cognitive load decreases during extended (six months) at-home use of an advanced neuromyoelectric prosthesis (Aim 3). Aim 3 will provide the first exploration of the cognitive effects of using an advanced prosthesis in a home setting for an extended period. Success in these aims will establish a fundamentally different yet essential pathway for assessing the viability of prosthesis advancements in a patient-centric manner. Documented effectiveness of sensory feedback and long-term use in prosthetic control is not only of scientific interest, but are also requisite for translating these advanced prosthetic technologies to clinical acceptance and use. Altogether, this project will provide methodologies that can be used in the upper-limb prosthesis community and beyond.