Neurodevelopment

项目摘要/摘要--项目4.神经发育 该项目的目标是为Bergia Brain项目的总体目标提供一个发展的视角 了解躯体视觉、嗅觉和视觉加工的实施。这些目标将得到以下帮助 对涉及的神经元的来源进行调查。已鉴定神经元发育起源的研究进展 这个项目基本上在40年前就停止了，这个项目填补了我们知识的空白。项目4将确定 胚胎细胞在中枢和外周神经系统中形成神经元的细胞。它将识别基因 使这些细胞独一无二，并使用该信息来识别驾驶所需监管信息 特定神经元中的荧光融合蛋白。这些见解将扩大我们对神经发生的理解 对于软体动物来说，这是一种相对研究较少的多样化的有机体，因此具有 揭示神经系统发育的新细胞和分子机制。

PROJECT SUMMARY / ABSTRACT – Project 4. Neurodevelopment The goal of this Project is to provide a developmental perspective to the overall goals of the Berghia Brain Project to understand the implementation of somatotopic, olfactory, and visual processing. These goals will be aided by investigation into the origin of the neurons involved. Work on the developmental origin of identified neurons essentially stopped forty years ago and this project fills that gap in our knowledge. Project 4 will identify the embryonic cells that give rise to neurons in the central and peripheral nervous systems. It will identify the genes that make these cells unique, and use that information to identify the regulatory information necessary to drive fluorescent fusion proteins in specific neurons. These insights will expand our understanding of neurogenesis to molluscs, a diverse clad of organisms that has been relatively understudied, and thus holds potential for uncovering novel cellular and molecular mechanisms for nervous system development.