Administration and Biostatistics Core

行政和生物统计核心(核心A)的目的是协调行政和财政 PPG的活动，为所有项目提供生物统计支助，并确保严格的实验 对所有项目进行设计和数据分析。林顿博士将负责监督Core A的所有职能。 赠款经理尼古拉斯·詹金斯将与林顿博士密切合作，提供财政监督和管理 PPG项目和核心的预算问题，包括遵守机构政策和 落实岗位奖励管理奖补政策。Jenkins先生将协助编制与赠款相关的预算 提交，包括竞标和非竞标续期。劳伦斯女士将负责财务方面的工作 预算的管理。她将监督并协调与格兰茨经理的沟通 和政务官。政务干事Maria Peng将编制每月预算报表 调查人员的项目和核心。她将负责PPG报告和行政管理 服务核心和项目的资金。劳伦斯女士和行政助理巴特库斯女士将 共同负责为所有PPG项目生成设备和试剂的采购订单 核心，以及支出对账。Bartkus女士还将帮助安排PPG的每月会议。 项目负责人、调查员和核心负责人，组织研讨会、与顾问会面并处理PPG 相关旅行。她将确保所有人类受试者和动物用途的文件都是最新的。生物统计学 核心A部分将为所有项目和调查人员提供统计专业知识，以确保严谨和 所有PPG项目的重现性。叶和杜博士将继续与项目负责人密切合作，并将 向所有PPG调查人员提供最先进的统计支持。确保统计 重复性，对于执行的每个与PPG相关的分析，将以HTML或PDF格式提供统计报告 生成，它将记录R编程代码和分析中使用的任何模拟种子。 此外，所有模型开发程序都将使用交叉验证或引导程序进行内部验证 方法：研究方法。生物统计核心支持所有4个项目。生物信息学支持将在核心D提供： 非编码RNA和生物信息学核心。

The purpose of the Administrative and Biostatistics Core (Core A) is to coordinate the administrative and fiscal activities of the PPG, to provide biostatistics support for all of the Projects, and to ensure rigorous experimental design and data analysis for all the Projects. Dr. Linton will provide oversight for all functions of Core A. Mr. Nicholas Jenkins, Grants Manager, will work closely with Dr. Linton to provide fiscal oversight and management of the budgetary aspects of the PPG’s Projects and Cores, including compliance with institutional policy and implementation of grant policy for post award management. Mr. Jenkins will assist with budgets related to grant submissions, including competing and noncompeting renewals. Ms. Lawrence will oversee the financial aspects of the administration of the budget. She will supervise and coordinate communication with the Grants Manager and the Administrative Officer. Maria Peng, Administrative Officer, will prepare monthly budget statements for the Projects and Cores for the Investigators. She will be responsible for PPG reports and administration of finances for the service Cores and the Projects. Ms. Lawrence and Ms. Bartkus, the administrative assistant, will be jointly responsible for generating purchase orders for equipment and reagents for all of the PPG Projects and Cores, and for expenditure reconciliation. Ms. Bartkus will also help with arranging the monthly meetings of PPG Project Leaders, investigators and Core Leaders, organize seminars, meetings with advisors and handle PPG related travel. She will ensure that all human subject and animal use documentation is current. The Biostatistics portion of Core A will provide statistical expertise for all projects and investigators to ensure rigor and reproducibility for all PPG projects. Drs. Ye and Du will continue to work closely with project leaders and will be available to all PPG investigators to provide state-of-the-art statistical support. To ensure statistical reproducibility, for each PPG-associated analysis performed, a statistical report in HTML or PDF format will be generated, which will document the R programming codes and any simulation seeds used in the analysis. Additionally, all model development procedures will be internally validated using cross-validation or bootstrap methods. The Biostatistics Core supports all 4 Projects. Bioinformatics support will be provided in Core D: The Non-Coding RNA and Bioinformatics Core.