Medical Genetics Research Training Grant

医学领域正在经历一场基因组学革命。需要培训内科科学家和 不同背景的研究人员在基因组和遗传方法学方面经验丰富，并能够翻译 从基因组学到临床治疗的基础科学发现从未像现在这样伟大。这一行动的主要目标是 博士后研究培养计划是培养未来医学遗传学和基因组学的领军人物 将从各种培训途径中脱颖而出，拥有不同数量的研究经验。博士后 医学博士或医学博士学位，医学遗传学，儿科学，医学， 精神病学、病理学和其他专业领域将有资格获得这笔培训补助金的支持。资金用于 寻求每年5个培训机会。临床培训年限(一般为分类医学遗传学第一年 受训人员和1-3年儿科和医学遗传学联合受训人员)由佩雷尔曼基金会资助 宾夕法尼亚大学医学院和费城儿童医院 (CHOP)，而整个培训计划的研究年度的资金则从这笔培训补助金中寻求。 在此培训助学金支持的医学遗传学研究奖学金年度中，该研究员致力于 至少85%的精力在基础科学实验室进行研究。研究机会极其多样化 在宾夕法尼亚大学CHOP/UP的6个核心部门的42个学院的实验室接受培训。研究领域可能 涵盖那些影响人类遗传学的领域，包括但不限于：基因组学、分子 遗传学、细胞基因组学、生化遗传学、表观遗传学、线粒体遗传学、发育生物学、 细胞生物学、生物信息学、系统生物学、药物遗传学、基因治疗等。在.期间 在研究年，学员还参加研讨会课程，参加期刊俱乐部，研究会议，以及 科室研究撤退，并开展最低限度的临床活动，不超过15%的努力。培训 这份申请书要求提供2-3年研究的津贴。医学博士实习生很可能需要 进一步的研究培训(不在此培训补助金的范围内)，可通过额外的 博士后研究经验或受保护的教职任命，并得到前辈的大量指导 教职员工。本建议书中概述的培训计划建立在我们过去的成功记录基础上，并 致力于招募一批才华横溢的多元化博士后实习生，为富有和支持 研究环境，并通过严格的培训、指导和监督计划发展未来 医学遗传学和基因组学领域的内科科学家领袖。

The field of medicine is experiencing a genomics revolution. The need to train physician scientists and investigators of diverse backgrounds experienced in genomic and genetic methodologies and able to translate basic science discoveries in genomics into clinical care has never been greater. The major goal of this postdoctoral research training program is to train the future leaders of Medical Genetics and Genomics who will emerge from a variety of training pathways with varying amounts of research experience. Postdoctoral trainees with M.D. or M.D., Ph.D. degrees with clinical training in Medical Genetics, Pediatrics, Medicine, Psychiatry, Pathology, and other specialty areas will be eligible for support from this training grant. Funding for 5 training slots per year is sought. The clinical training years (typically year 1 for Categorical Medical Genetics trainees and years 1-3 for combined Pediatric and Medical Genetics trainees) is funded by the Perelman School of Medicine at the University of Pennsylvania (UPenn) and The Children’s Hospital of Philadelphia (CHOP), while funds for the research years of the overall training program are sought from this training grant. During the Medical Genetics Research Fellowship years supported by this Training Grant, the fellow devotes a minimum of 85% effort to research in a basic science laboratory. Research opportunities are extremely diverse with training in the laboratories of 42 Faculty from 6 core departments at CHOP/UPenn. Fields of research may encompass those areas that impact human genetics including, but not limited to: genomics, molecular genetics, cytogenomics, biochemical genetics, epigenetics, mitochondrial genetics, developmental biology, cellular biology, bioinformatics, systems biology, pharmacogenetics, gene therapy and others. During the research years, the trainee also takes seminar courses, attends journal clubs, research meetings, and departmental research retreats, and carries out minimal clinical activities, not to exceed 15% effort. Training stipends for the 2-3 years of research are requested in this application. The M.D. trainee will likely require further research training (not covered by this training grant), which might be acquired through an additional postdoctoral research experience or a protected faculty appointment with considerable mentoring from a senior faculty member. The training program outlined in this proposal is built on our past rack record of success and is committed to recruiting a diverse group of highly talented postdoctoral trainees to a rich and supportive research environment and through a rigorous program of training, mentorship and oversight develop the future physician-scientist leaders in Medical Genetics and Genomics.