Multimodal Imaging in Frontotemporal Degeneration

项目总结 这是霍华德·罗森博士第一次申请K24奖项，他是一名行为神经学家 加州大学旧金山分校。罗森博士的研究重点是早期识别和纵向识别 追踪非典型神经退行性疾病，特别是额颞部痴呆(FTD)。这项工作需要 位于加州大学旧金山分校的记忆和衰老中心，这是一个致力于研究、护理和 关于神经退行性疾病的教育。在这个项目的第一个周期中，罗森博士担任21个项目的导师 个人在不同的培训阶段，并实现了他的目标，扩大对家庭形式的研究 FTD的。他通过与加州大学旧金山分校的合作，帮助实施了诊断FTD的新战略 精神病学系。罗森博士还通过领导 为一项名为全球脑健康研究所的新培训计划制定教育课程， 该中心的使命是通过培训来自 各式各样的学科。在K24的持续资助下，罗森博士将继续领导研究和 在MAC进行培训，重点是改进测量FTD变化的方法，用于临床试验和 扩大与加州大学旧金山分校精神病学的合作。他将通过以下途径提高自己作为调查员的专业水平 加州大学旧金山分校的精选课程和与专家同事的合作。

PROJECT SUMMARY This is the first renewal application for a K24 award for Dr. Howard Rosen, a behavioral neurologist at the University of California, San Francisco. Dr. Rosen’s research focuses on early recognition and longitudinal tracking of atypical neurodegenerative diseases, in particular frontotemporal dementia (FTD). The work takes place at the UCSF Memory and Aging Center, a large multidisciplinary group dedicated to research, care and education in neurodegenerative diseases. In the first cycle of this project, Dr. Rosen served as a mentor for 21 individuals at various stages of training and accomplished his goals of expanding his research on familial forms of FTD. He helped to implement new strategies for diagnosis of FTD through collaboration with the UCSF Department of Psychiatry. Dr. Rosen also expanded the reach of his educational expertise by leading development of the educational curriculum for a new training program called the Global Brain Health Institute, the mission of which is to address worldwide threats to brain health through training of professionals from a variety of disciplines. With continued K24 funding, Dr. Rosen will continue his leadership of research and training at the MAC, focusing on improving methods for measuring change in FTD for use in clinical trials and expanding collaboration with UCSF Psychiatry. He will improve his expertise as an investigator through selective coursework and collaboration with expert colleagues at UCSF.