06 Cancer Control and Population Sciences Program

06癌症控制和人口科学（CCPS） 摘要 CCPS计划的总体科学目标是通过假设驱动的 观察性（流行病学）和干预性转化研究，跨越实验室工作台， 床旁和最终，整个社区（即，“长凳到战壕”）。这一目标指导了41项研究。 高生产力的科学家谁是该计划的成员-研究是由超过1500万美元的支持 在赠款资金。考虑到UAB CCC位于南部腹地，一个以贫困和大面积贫困为特征的地区， 服务不足的非洲裔美国人和阿巴拉契亚白人的选区，我们的首要主题 该计划旨在消除癌症连续体中的健康差异，从原发性癌症风险到改善的癌症风险。 癌症存活率此外，由于亚拉巴马是肥胖率最高的州之一， 在我们的集水区，许多最流行的癌症都与超重和肥胖有关，我们 一直致力于研究能量平衡和癌症。CCPS计划是 由一批多学科研究人员组成，他们在14个系和6个系担任教职。 学校和世卫组织在分子和遗传流行病学、健康和癌症领域拥有广泛的专业知识 结果，癌症健康差异，行为科学，营养和肥胖，生活质量和生命终结 护理和癌症生存研究。与历史上的黑人学院/大学的长期合作伙伴关系， 我们的区域，莫尔豪斯医学院和塔斯基吉大学提供了一个合作的学术 该网络延伸到南方腹地，并带来了研究和培训机会， 独立资助，并在顶级期刊上发表论文。CCPS计划提供了一个 促进新成员和初级成员培训的组织基础设施，以及 所有成员之间的互动。CCPS还创建了一个活动界面， 实验室和临床科学的整合，以人口为基础的行为科学研究。 在这个资助周期内，我们发表了361篇稿件，其中25%是计划内的，18%是计划外的。 68%是机构间的。重要的是，许多论文和赠款资助的研究结果 来自与其他NCI指定癌症中心的研究人员的合作，如Fred哈钦森，MD 安德森，纪念斯隆凯特林，莫菲特，马约，华盛顿大学圣路易斯分校，达纳法伯和 亚利桑那大学、加州大学和科罗拉多大学。

06 CANCER CONTROL AND POPULATION SCIENCES (CCPS) PROGRAM ABSTRACT The overall scientific goal of the CCPS Program is to reduce the burden of cancer through hypothesis-driven observational (epidemiological) and interventional translational research that spans the laboratory bench to the bedside and ultimately, the community at large (i.e., “bench to trench”). This goal guides the research of 41 highly productive scientists who are members of this Program – research that is supported by over $15 million in grant funding. Given UAB CCC's location in the Deep South, a region marked by poverty and large constituencies of underserved African-Americans and Appalachian Whites, an overarching theme of our program is to eliminate health disparities across the cancer continuum, from primary cancer risk to improved cancer survivorship. Additionally, since Alabama is a state with one of the highest rates of obesity, and that many of the most prevalent cancers within our catchment area are associated with overweight and obesity, we have worked diligently to develop a research focus in energy balance and cancer. The CCPS program is comprised of a cadre of multidisciplinary investigators who hold faculty appointments in 14 departments and 6 schools and who have broad expertise in areas of molecular and genetic epidemiology, health and cancer outcomes, cancer health disparities, behavioral science, nutrition and obesity, quality of life and end-of-life care, and cancer survivorship research. Long-term partnerships with Historically Black Colleges/Universities in our region, i.e., Morehouse School of Medicine and Tuskegee University provide a collaborative academic network that stretches across the Deep South and has resulted in research and training opportunities that are independently funded and have yielded publications in top-tier journals. The CCPS Program provides an organizational infrastructure that facilitates training for new and junior members, and active forums for collaborative interaction among all of its members. The CCPS also creates an active interface that enhances the integration of laboratory and clinical sciences, with population-based and behavioral science research. During this funding cycle, we have published 361 manuscripts of which 25% were intra-programmatic, 18% inter-programmatic, and 68% inter-institutional. Importantly, many papers and grant-funded research resulted from collaborations with investigators at other NCI-designated cancer centers, such as Fred Hutchinson, MD Anderson, Memorial Sloan Kettering, Moffitt, Mayo, Washington University in St. Louis, Dana-Farber and the Universities of Arizona, California, and Colorado.