Modification and Renovation of Vivarium for the Advancement of Institutional Biomedical Research

拟议中的项目将翻新北卡罗来纳农业技术州立大学(NCA&T) 已有38年历史的间隔室，用作核心研究设施，为大学社区和 北卡罗来纳州中部的山前三合会地区。这次翻修是非常必要的，以解决间隔室的 结构和设计问题，使其具有挑战性，以满足生物医学研究人员的需求 在我们机构中人数正在增加的群体。所要求的资金将有助于推动这一进程 生物医学研究的增加，打破了限制教师提交 联邦拨款提案用于动物研究，并限制了我们的进一步扩展 科研院所的生物医学研究企业。由于隔膜的过时地位，我们的 研究人员正在使用其他设施或改变他们的研究议程，以替代模式。至 扭转这一趋势，并与大学的战略计划和获得R1地位的既定意图保持一致， 项目目标是(1)翻新和重新设计现有的隔膜，以提供一个现代化的 环境控制单元，具有降噪和高效的笼子清洗设施和交通 模式和(2)创造一个靠近屏障的设施，有固定的排气通风笼子和生物安全 橱柜。拟议翻新的长期影响将使生物医学、寿命得以扩大 NCA&T和皮埃蒙特三合会地区的科学和农业研究，这是一个不断增长的 生物科学、制药和医疗保健领域的公司数量；并增加 本科生、博士和博士后研究培训，以增加地区、全州和 生物医学科学和职业领域的国家多样性。 隔室的翻新将通过提供 在核心研究动物设施的校园内开展生物医学研究项目所需的资源 而不是在其他设施中寻求动物住所和辅助支持。翻新后的设施还将 通过鼓励教职员工寻求有针对性的外部资金来支持提高研究生产率 扩大他们的生物医学研究组合，纳入动物模型，并通过促进招聘 具有生物医学研究兴趣的新研究人员。此外，该项目将帮助我们实现 我们实现AAALAC认证的长期目标。 根据美国法典第42章第283k(C)(2)节的四项标准，NCA&T宣布其为 新兴卓越(IEE)。翻新的隔膜将帮助NCA&T提升其地位，从NIH- 将IEE指定为研究密集型机构。

The proposed project will renovate North Carolina Agricultural and Technical State University’s (NCA&T) 38- year-old vivarium for use as a core research facility serving the university community and the Piedmont Triad region in central NC. This renovation is critically needed to address the vivarium’s structural and design issues that make it challenging to meet the needs of biomedical researchers, a group whose numbers are increasing at our institution. The requested funding will help drive this increase in biomedical research, breaking the Catch-22 predicament that limits faculty submission of federal grant proposals for research with animal subjects and constrains further expansion of our institution’s biomedical research enterprise. As a result of the vivarium’s outdated status, our researchers are using other facilities or changing their research agendas to alternative models. To reverse this trend and align with the university’s strategic plan and stated intent to attain R1 status, the project goals are to (1) renovate and redesign the existing vivarium to provide a modern environmentally-controlled unit, with noise reduction and an efficient cage washing facility and traffic pattern and (2) to create a near barrier facility with fixed exhaust ventilated cages and biological safety cabinets. Long-term impact of the proposed renovation will enable the expansion of biomedical, life science, and agricultural research at NCA&T and the Piedmont Triad region, which is home to a growing number of companies in the biosciences, pharma, and healthcare; and increase the advancement of undergraduate, doctoral and post-doctoral research training to increase regional, statewide and national diversity within biomedical sciences and careers. Renovation of the vivarium will enhance research programs across the institution by providing the resources needed to conduct biomedical research projects on campus in a core research animal facility versus seeking animal housing and ancillary support at other facilities. The renovated facility will also support increased research productivity by encouraging faculty to seek targeted external funding to grow their biomedical research portfolios incorporating animal models and by promoting recruitment of new research faculty with biomedical research interests. Additionally, the project will help us accomplish our long-term goal of achieving AAALAC accreditation. Per the four criteria at U.S.C. 42 Section 283k(c)(2), NCA&T declares its status as an Institution of Emerging Excellence (IEE). The renovated vivarium will help NCA&T elevate its status from an NIH- designated IEE to a research-intensive institution.