MFMU Network Protocols

项目总结/摘要 犹他州大学一直是NICHD母胎医学单位中最具生产力的地点之一 （MFMU）网络在过去的25年里，贡献了许多概念和协议， 良好特征的研究参与者，高质量的研究数据和多个重要的二次分析 从而产生国家介绍和奖励。本申请的具体目的是允许 正在进行的MFMU网络协议，在当前资助周期结束后（3月31日）长达四年 2021年）。犹他州中心已向网络指导委员会提交了25份提案，其中15份 已进入全面协议状态。犹他州中心一直是领先的网络中心之一， 筛选、招募和数据质量。Torri梅斯医学博士自2019年初以来一直担任犹他州中心PI。在 除了承担众多的网络管理职责外，她还不知疲倦地工作，以确保 犹他州大学-山间医疗保健合作继续是互利的。二十六 董事会认证/董事会合格的MFM部门教师加上6 MFM研究员提供24/7/365覆盖的5 参与的犹他州医院。5家参与医院每年约有18，000例分娩（40%）， 在犹他州交付）。在过去25年中，MFMU网络研究招募的人口 年是北方犹他州城市走廊人口的代表。提供支持信 所有医院的新生儿重症监护室主任和代表性的统计数据也提供了。犹他州大学 发展评估中心为MFMU网络和犹他州新生儿提供研究随访 研究网络协议。所有5家参与医院都有长期有效的数据系统。 29名研究人员在5家医院和100多个办公室从事MFMU网络协议的研究 沿着犹他州城市走廊的妇女健康提供者。这些人都是敬业的临床研究人员， 具有低周转率。犹他州的大学是热情致力于继续参与， NICHD MFMU网络，经多封支持信证实。 梅斯博士、埃斯普林博士和瓦尔纳博士经过证明的持续能力， 社区产科提供者和吸引/留住优秀的临床研究人员是 成功的犹他州网站，并将继续通过完成正在进行的网络协议，如果 选择犹他州中心继续参与网络。

PROJECT SUMMARY/ABSTRACT The University of Utah has been one of the most productive sites in the NICHD Maternal-Fetal Medicine Units (MFMU) Network over the past 25 years, contributing numerous concepts and protocols, large numbers of well-characterized study participants, high-quality research data, and multiple important secondary analyses resulting in national presentations and awards. The specific aim of this application is to allow continuation of ongoing MFMU Network protocols for up to four years beyond the end of the current funding cycle (31 March 2021). The Utah center has submitted 25 proposals to the Network Steering Committee, of which 15 have been advanced to full protocol status. The Utah center is consistently among the leading Network centers for screening, recruitment and data quality. Torri Metz MD has served as the Utah center PI since early 2019. In addition to has numerous Network administrative responsibilities, she has worked tirelessly to ensure that the University of Utah – Intermountain Healthcare collaboration continues to be mutually beneficial. Twenty-six Board-Certified/Board Eligible MFM Division faculty plus 6 MFM Fellows provide 24/7/365 coverage for the 5 participating Utah hospitals. The 5 participating hospitals represent ~18,000 deliveries per year (40% of the deliveries in the State of Utah). The population recruited into MFMU Network studies over the previous 25 years is representative of the population of the northern Utah urban corridor. Letters of support are provided from the NICU Directors at all hospitals and representative statistics are also provided. The University of Utah Developmental Assessment Center provides research follow-up for MFMU Network and Utah Neonatal Research Network protocols. Long-standing functional data systems exist in all 5 participating hospitals. Twenty-nine research personnel work on MFMU Network protocols in 5 hospitals and the offices of over 100 women’s health providers along the Utah urban corridor. These individuals are dedicated clinical researchers, with a low turn-over rate. The University of Utah is enthusiastically committed to continued participation in the NICHD MFMU Network, as confirmed by multiple letters of support. The proven and continuing ability of Drs. Metz, Esplin and Varner to enlist wide-spread participation by community obstetric providers and to attract/retain an excellent clinical research staff are major factors in the success of the Utah site and will continue through the completion of ongoing Network protocols, should the Utah center be selected for continued Network participation.