Improvements to the Regional Biocontainment Research Facilities at the University of Missouri
Improvements to the Regional Biocontainment Research Facilities at the University of Missouri
批准号:
10394455
负责人:
Christian L. Lorson
金额:
$332.73万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-09-23 至 2025-02-28
关键词:
AirAnimalsAreaArthropodsCarbon DioxideCommunicationContainmentContractorDecontaminationElevatorEquipmentGasesHydrogen PeroxideImmunologyInformation TechnologyLiquid substanceMaintenanceMechanicsMissouriModernizationNitrogenPhilosophySafetySecuritySeriesSteamSystemUniversitiesVacuumWalkingcostimprovedrepairedresearch facility
中文摘要
项目摘要/摘要
我们在接近这个机会时使用的核心理念是不包括例行公事
维护或维修,目前由我们的设施管理专家提供。相反,我们
将重点放在被视为“改进”的子系统维修或升级上。改进并不是
由设施管理部门例行执行,无需支付相关成本或通过外部
承包商。因此,我们建议的范围仅限于设施改善。概括地说,这些改进
(或我们需要的)分为三个主要的子领域,如下所列,而其他技术细节
都是在现代化计划中提供的。我们已经确定了一系列高优先级目标,每个请求
将在以下各节中详细介绍。
空间:节肢动物隔离套间、动物房间、更衣室和
屋顶系统。翻新我们的更衣室空间,更换我们酒店上方的平房部分
安保办公室和休息室,我们机械空间的油漆和石膏板维修,我们的
ABSL3空间采用Arcoplast天花板,并对我们的节肢动物隔离套房进行了翻新。
设施子系统升级/改进。简而言之,这些子系统包括以下内容:
电梯,升级到我们的外部围栏和大门,安全服务器和摄像头升级,升级到我们的
菲尼克斯阀门和Metasys控制器,升级我们的蒸汽锅炉燃烧器系统,燃气系统升级
包括液氮、二氧化碳、房屋真空和压缩空气子系统,并增加了一套新的
通信系统。
更换/改进核心设备。以支持的功能和安全性
我们已要求改善设施,并确定了几件设备。请求的设备
包括一个新的污水净化系统(EDS),4个二级生物安全柜;2个蒸气氢气
过氧化物区去污系统;免疫学核心和空气生物学的升级/更换
核心;信息技术核心改进;以及2个无需预约的节肢动物环境室。
英文摘要
PROJECT SUMMARY/ABSTRACT
The central philosophy we used in approaching this opportunity was to not include items of routine
maintenance or repair, which are currently provided by our experts in facilities management. Instead, we
have focused on subsystem repairs or upgrades that are considered “betterments”. Betterments are not
routinely performed by facility management without an associated cost or without going through an external
contractor. Therefore, the scope of our proposal is limited to facility betterments. Broadly, the betterments
(or what we need) are divided into three major subareas as listed below while additional technical details
are provided in the Modernization Plan. We have identified a series of high priority targets and each request
is detailed within the following sections.
SPACES: REMODELING OF ARTHROPOD CONTAINMENT SUITE, ANIMAL ROOMS, CHANGE ROOMS AND
ROOF SYSTEM. Renovations of our change room spaces, replacement of the flat room section above our
security office and breakroom, painting and drywall repairs in our mechanical spaces, upgrades of our
ABSL3 space with Arcoplast ceilings and renovations to our arthropod containment suite.
FACILITY SUBSYSTEM UPGRADES/BETTERMENTS. Briefly, these subsystems include the following: an
elevator, upgrades to our outer fence and gates, security server and camera upgrades, upgrades to our
Phoenix valves and Metasys controllers, upgrades to our steam boiler burner systems, gas system upgrades
including liquid nitrogen, CO2, house vacuum and compressed air subsystems, and addition of a new suite
communication system.
REPLACEMENT/BETTERMENT OF CORE EQUIPMENT. To support the functionality and safety of the
improved facility we have requested and identified several pieces of equipment. Requested equipment
includes a new effluent decontamination system (EDS), 4 class II biosafety cabinets; 2 vaporous hydrogen
peroxide area decontamination systems; upgrades/replacements for the Immunology Core and Aerobiology
Core; information technology core improvements; and 2 walk-in arthropod environmental chambers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Improvements to the Regional Biocontainment Research Facilities at the University of Missouri
-
批准号:10631453
-
项目类别:
-
资助金额:$234.07万
-
财政年份:2021
-
负责人:Christian L. Lorson
-
依托单位:
Novel SMARD1 Mouse Models: Characterization and Evaluation of Potential Therapeutic Targets
-
批准号:10558457
-
项目类别:
-
资助金额:$34.77万
-
财政年份:2020
-
负责人:Christian L. Lorson
-
依托单位:
Novel SMARD1 Mouse Models: Characterization and Evaluation of Potential Therapeutic Targets
-
批准号:10333249
-
项目类别:
-
资助金额:$34.77万
-
财政年份:2020
-
负责人:Christian L. Lorson
-
依托单位:
Novel SMARD1 Mouse Models: Characterization and Evaluation of Potential Therapeutic Targets
-
批准号:10087982
-
项目类别:
-
资助金额:$34.72万
-
财政年份:2020
-
负责人:Christian L. Lorson
-
依托单位:
Novel SMARD1 Mouse Models: Characterization and Evaluation of Potential Therapeutic Targets
-
批准号:9973984
-
项目类别:
-
资助金额:$33.87万
-
财政年份:2020
-
负责人:Christian L. Lorson
-
依托单位:
Evaluating AAV-mediated gene replacement for Spinal Muscular Atrophy with Respiratory Distress 1
-
批准号:9034843
-
项目类别:
-
资助金额:$22.22万
-
财政年份:2015
-
负责人:Christian L. Lorson
-
依托单位:
Monoallelic repair of expanded huntingtin by trans-splicing
-
批准号:8048355
-
项目类别:
-
资助金额:$22.73万
-
财政年份:2010
-
负责人:Christian L. Lorson
-
依托单位:
Monoallelic repair of expanded huntingtin by trans-splicing
-
批准号:8129437
-
项目类别:
-
资助金额:$18.56万
-
财政年份:2010
-
负责人:Christian L. Lorson
-
依托单位:
Funding for FightSMA Researchers' Conference in Washington, DC, April 2008
-
批准号:7487724
-
项目类别:
-
资助金额:$3.3万
-
财政年份:2008
-
负责人:Christian L. Lorson
-
依托单位:
Stimulating SMN2 exon 7 inclusion with short RNAs
-
批准号:7945390
-
项目类别:
-
资助金额:$25.66万
-
财政年份:2007
-
负责人:Christian L. Lorson
-
依托单位:
Stimulating SMN2 exon 7 inclusion with short RNAs
-
批准号:7479730
-
项目类别:
-
资助金额:$30.25万
-
财政年份:2007
-
负责人:Christian L. Lorson
-
依托单位:
Stimulating SMN2 exon 7 inclusion with short RNAs
-
批准号:8103021
-
项目类别:
-
资助金额:$25.4万
-
财政年份:2007
-
负责人:Christian L. Lorson
-
依托单位:
Stimulating SMN2 exon 7 inclusion with short RNAs
-
批准号:7622157
-
项目类别:
-
资助金额:$25.92万
-
财政年份:2007
-
负责人:Christian L. Lorson
-
依托单位:
Stimulating SMN2 exon 7 inclusion with short RNAs
-
批准号:7315340
-
项目类别:
-
资助金额:$30.87万
-
财政年份:2007
-
负责人:Christian L. Lorson
-
依托单位:
Determinants that regulate splicing of SMN
-
批准号:6757828
-
项目类别:
-
资助金额:$34.33万
-
财政年份:2001
-
负责人:Christian L. Lorson
-
依托单位:
Determinants that regulate splicing of SMN
-
批准号:7437336
-
项目类别:
-
资助金额:$32.66万
-
财政年份:2001
-
负责人:Christian L. Lorson
-
依托单位:
Determinants that regulate splicing of SMN
-
批准号:7810632
-
项目类别:
-
资助金额:$10.99万
-
财政年份:2001
-
负责人:Christian L. Lorson
-
依托单位:
Determinants that regulate splicing of SMN
-
批准号:7432216
-
项目类别:
-
资助金额:$7.16万
-
财政年份:2001
-
负责人:Christian L. Lorson
-
依托单位:
Determinants that regulate splicing of SMN
-
批准号:7470302
-
项目类别:
-
资助金额:$3.5万
-
财政年份:2001
-
负责人:Christian L. Lorson
-
依托单位:
Determinants that regulate splicing of SMN
-
批准号:7142158
-
项目类别:
-
资助金额:$33.64万
-
财政年份:2001
-
负责人:Christian L. Lorson
-
依托单位:
海外基金