RESHAIR4LIFE: Implementation research on the tailored, multidisciplinary NCD prevention package FRESHAIR4LIFE: Targeting tobacco and air pollution exposure in mid- to late adolescents in disadvantaged populations

非传染性疾病(NCD)是健康不佳和过早死亡的主要原因。尽管我们知道如何减轻风险因素和预防非传染性疾病，但我们未能应用这一知识，特别是在弱势群体中。FA4LIFE旨在弥合这一翻译差距，并获得知识、资源和能力，以优化针对弱势群体青少年的多层次、基于证据的烟草和空气污染(AP)暴露预防一揽子计划的实施。为此，FA4LIFE将在五个国家开展工作：希腊、吉尔吉斯共和国、巴基斯坦、罗马尼亚和乌干达。所有这些国家都面临着沉重的非传染性疾病负担，但它们的背景有很大不同。这些差异提供了获得实施知识和资源的机会，这些知识和资源可以根据世界各地的情况进行推断。FA4LIFE的所有活动都得到双重能力建设的支持：建立青年宣传和专业领导力。在每个环境中，我们将：1.执行情景分析(包括可负担性)并建立可持续的利益相关者参与团队2.使用预防调色板方法共同创建针对中晚期青少年烟草和AP暴露的定制、循证的FA4LIFE预防方案，考虑到公平性3.实施、评估和反复改进FA4LIFE预防方案4.通过青年倡导数字倡议、社区领导学校和教师教学计划，通过建设双重能力来优化可持续实施和公平影响一项强有力和创新的传播、利用和传播计划，包括FA4LIFE行动案例、FA4LIFE实施工具箱和广泛的青年宣传信息社交媒体战略，将促进提升和最大限度地提高对非传染性疾病负担的全球影响，特别是在弱势群体中最危险或最需要帮助的青少年中。

Non-Communicable Diseases (NCD) are the leading cause of ill health and premature mortality. Although we know how to mitigate risk factors and prevent NCDs, we have failed to apply this knowledge, especially in disadvantaged populations. FA4LIFE aims to bridge this translational gap, and gain knowledge, resources and capacity to optimize implementation of multi-level, evidence-based tobacco and air pollution (AP) exposure prevention packages targeting adolescents in disadvantaged populations. To do so, FA4LIFE will work in five countries; Greece, the Kyrgyz Republic, Pakistan, Romania and Uganda. All face a high NCD burden, but their contexts differ significantly. These differences provide opportunity to gain implementation knowledge and resources that can be extrapolated to settings worldwide. All FA4LIFE activities are supported by dual capacity building: creating youth advocacy and professional leadership. In each setting, we will: 1. Perform situational analysis (incl. affordability) and establish sustainable stakeholder engagement teams 2. Use the Prevention palette method' to co-create a tailored, evidence-based FA4LIFE prevention package targeting tobacco and AP exposure in mid- to late adolescents, mindful of equity 3. Implement, evaluate and iteratively refine the FA4LIFE prevention package 4. Optimize sustainable implementation and equitable impact by building dual capacity, via youth advocacy digital initiatives, community leadership schools and Teach-the-Teacher programs. A robust and innovative dissemination, exploitation and communication plan, including the FA4LIFE Case For Action, the FA4LIFE implementation toolbox, and broad youth advocacy-informed social media strategy will promote upscaling and maximize global impact on NCD burden, especially in those adolescents most at risk or in need in disadvantaged populations.