Developmental Psychology Training Grant

项目摘要：美国青年成长于更加多变的环境中。这些 在整个生命过程中，环境都会对健康和福祉产生深远的积极和消极影响。 然而，人们对经济、文化、种族和家庭背景如何成为生物学背景知之甚少。 以及在发育过程中这种与生物学的相互作用如何影响发育的轨迹 和健康结果。知识稀少的部分原因是，很少有调查人员拥有 成功解决这些问题所需的三个领域，即 背景、人类神经生物学和先进的研究方法。我们提出了一个培训计划，这将有助于 填补这一空白。目标是培养一批优秀的研究生和博士后研究员。 知识支柱：(1)环境发展科学；(2)人类神经生物学，包括大脑 发展、基因组学和内分泌功能；以及(3)先进的研究方法(例如，预测性 分析、机器学习、比较方法)。这种交叉训练，是建立在 对基本发育过程的理解，将使研究人员处于有利地位，进行切割- 前沿研究，促进关于神经生物学因素如何与环境相互作用以影响的知识 跨多个领域的开发。接受这一培训的人将满足日益增长的 发展科学家将神经科学的观点和方法整合到他们的 研究并拥有成功的、协作的、跨学科工作所需的技能 神经生物学、背景和行为发展。对这种专业知识的需求很旺盛，预计 考虑到接受过跨学科培训的人很少，而且最近令人兴奋的是 我们对神经生物学在心理发展中的作用的理解的进展。我们请求提供资金以 每年支持4名博士后进修生和2名博士后进修生。学员将参加为期两年的系列培训。 课程和直接的基于导师的研究培训，使他们能够整合背景、人类 神经生物学和先进的方法学。每名学员将有三名导师，内容包括(1)发展 背景，(2)人类神经生物学，和(3)先进的方法学。培训计划将设在 发展领域(心理学系)，有22名参与其中的教职员工。一个 额外的力量是，培训补助金包括来自其他单位的13名教职员工，其中包括 遗传学、生物心理学、认知和认知神经科学、语言学、儿科学和精神病学。这个 培训将利用密歇根大学丰富的资源，包括广泛的综合培训 研究和高级方法/统计课程。培训计划将为博士后和 博士后将在环境和人类神经生物学的发展科学研究中架起桥梁 以确定社会环境如何与遗传学和大脑相互作用来指导发育。

PROJECT SUMMARY: American youth are growing up in more contextually varied circumstances. These circumstances profoundly impact health and well-being, both positively and negatively across the life course. However, little is known about how economic, cultural, ethnic and family contexts become biologically embedded and how this interaction with biology during development influences trajectories of developmental and health outcomes. Part of the reason for the sparse knowledge is that few investigators have expertise in the three domains necessary to successfully grapple with these questions, namely, developmental science of context, human neurobiology, and advanced research methods. We propose a training program that will help fill this gap. The objective is to train an outstanding cohort of graduate students and postdoctoral fellows on 3 pillars of knowledge: (1) developmental science of context; (2) human neurobiology, including brain development, genomics, and endocrine function; and (3) advanced research methods (e.g., predictive analytics, machine learning, comparative approaches). This cross-training, which is predicated on an understanding of basic developmental processes, will produce researchers well positioned to conduct cutting- edge research that advances knowledge about how neurobiological factors interact with contexts to influence development across multiple domains. Those who receive this training will meet the growing demand for developmental scientists who integrate neuroscience perspectives and methods into their programs of research and possess the requisite skills for successful, collaborative, interdisciplinary work at the interface of neurobiology, context, and behavioral development. The demand for this expertise is strong and predicted to grow for years to come, given the paucity of individuals with the interdisciplinary training and the exciting recent advances in our understanding of the role of neurobiology in psychological development. We request funds to support 4 advanced predoctoral and 2 postdoctoral trainees each year. Trainees will engage in a 2-year series of courses and direct mentor-based research training that will allow them to integrate work on context, human neurobiology, and advanced methodology. Each trainee will have three mentors, covering (1) development of context, (2) human neurobiology, and (3) advanced methodology. The training program will be housed in the Developmental Area (within the Department of Psychology), which has 22 participating faculty members. An additional strength is that the training grant includes 13 faculty members from other units including Human Genetics, Biopsychology, Cognition and Cognitive Neuroscience, Linguistics, Pediatrics, and Psychiatry. The training will draw on the rich resources of the University of Michigan, including extensive training in integrative research, and courses in advanced methodology/statistics. The training program will prepare predoctoral and postdoctoral students to bridge research in the developmental science of context and human neurobiology in order to determine how the social environment interacts with genetics and the brain to guide development.