Developing the first 100% real food solution for tube feeding that is prescription ready: Improving access to a healthy balanced diet for all.

欧盟和北美有超过100万人（英国有7万人）需要长期管饲，通常通过直接插入胃中的管子使用配方奶粉。商业配方奶粉价格昂贵，每年花费NHS超过2亿英镑。配方奶喂养会导致各种副作用，包括恶心，呕吐，反流和便秘，影响生活质量和NHS预算。副作用可能导致住院治疗和长期依赖药物来控制它们。家庭混合食品的使用有了巨大的增长，“混合饮食”，作为配方奶粉的替代品。混合饮食副作用少，提高生活质量，减少对其他药物的依赖。至关重要的是，家庭混合食品对社会来说要便宜得多，每人每周花费10- 20英镑，而配方奶粉每人每周高达245英镑，为NHS减少了80%的成本。Wilbo的Blends的愿景是帮助每个有喂食管的人通过处方公平地获得真实的食物，以减少与饮食有关的不平等。我们预计通过减少配方奶粉、配方奶粉所需的药物和不必要的住院费用，可以在5年内实现每年节省3000万英镑。我们的公司是以用户为主导的“Wilbo的启发”。威廉，出生时有复杂的护理需求，像其他成千上万的人一样，成功地过渡到混合饮食，减少症状。这促使我们致力于支持管饲人群，并确保公平获得混合饮食。我们将为管饲人群（3岁以上）创造一套有机的，100%真实的食品，这将是第一个符合特殊医疗用途食品（FSMP）法规的产品，并获得边界物质咨询委员会（ACBS）的批准，并可按处方购买。Wilbo's将克服与产品配方、大规模生产和用户测试相关的技术复杂性，以满足：* FSMP耐受范围内的营养概况 * 卡路里密度\> 1.0千卡/毫升 * 足够平滑以通过饲管的稠度（IDDSI-level-3）。无菌包装可保存长达12个月，并可连接到注射器。该项目汇集了来自曼彻斯特创新生态系统的世界级学术，临床和商业化专业人士团队，与FSMP制造专家，营养师和监管顾问密切合作。我们的产品旨在支持管饲个体，但也可以被那些有不安全吞咽（称为吞咽困难）的口服饮食的人使用，包括中风和癌症患者。我们将努力推动所有人的访问。

Over 1 million individuals in the EU and North America (\>70,000 people in the UK) require long-term tube feeding, typically using formula through a tube inserted directly into the stomach. Commercial formula is expensive, costing the NHS more than £200million/year. Formula feeding can cause various side-effects including nausea, vomiting, reflux, and constipation which impact quality of life and NHS budgets. Side-effects can result in hospitalisation and a reliance on long-term medicines to manage them.There's been huge growth in the use of home-blended food, 'blended diet', as an alternative to formula. Blended diet has fewer side effects, improving quality of life and reducing reliance on other medicines. Crucially, home-blended food is far cheaper for society to sustain, costing £10-£20 per-person per-week, versus up to £245 per-person per-week for formula, an 80% reduction in costs for the NHS.Wilbo's Blends' vision is to help everyone with a feeding tube have equitable access to real food via prescription to reduce diet-related inequalities. We project \>£30m/year savings could be realised within 5-years by reducing formula, the medicines required alongside formula and the cost of unnecessary hospitalisations \[UoM, Health Economics\].Our company is user-led 'inspired by Wilbo'. William, born with complex care needs has, like thousands of others, successfully transitioned onto blended diet, reducing symptoms. This drives our commitment to support the tube feeding population and ensure equitable access to the blended diet.We will create a set of organic, 100% real food products for people (age3+) that are tube fed which will be the first to meet Food for Special Medical Purposes (FSMP) regulations, be approved by the Advisory Committee on Borderline Substances (ACBS) and be available on prescription.???Wilbo's will overcome technical complexities associated with formulating the products, manufacturing at scale and testing with users to meet:* Nutritional profile within FSMP tolerances* Calorie density \>1.0kcal/ml* A consistency that is smooth enough to pass through a feeding tube (IDDSI-level-3).* Sterile packaging that is shelf-stable for up to 12months and can connect to a syringe.This project brings together a world-class team of academic, clinical and commercialisation professionals from across Manchester's innovation ecosystem, working closely with FSMP manufacturing specialists, dietitians and regulatory consultants.Our products are designed to support tube fed individuals, but they can also be accessed by people with an oral diet who have an unsafe swallow (called dysphagia), including stroke and cancer patients. We will work to drive access for all.