Core 1: Administrative and Bioinformatics Core

摘要 博士巴特拉将领导行政和生物信息学核心（ABC）作为项目总监。巴特拉博士 将监督该计划的科学和行政活动，并主持P01执行委员会 委员会，包括所有研究项目负责人和共享核心资源主任（霍林斯沃思博士， Singh，Jain，and Thayer）.该团队将共同促进研究之间的沟通和合作， 项目和共享资源核心并监控和评估进展。巴特拉博士每周都会和研究人员会面 项目负责人和共享核心资源主任，他和他的工作人员将担任编辑审查/结算 存放POI活动产生的所有出版物。该核心将规划和协调定期研讨会， 将包括项目负责人、核心主任和调查员。这些研讨会将成为每月 通过其他胰腺癌网络计划（SPORE、EDRN）组织的胰腺癌计划 CVC和TMEN）。核心A将鼓励、促进和协调PPG研究者参与 有关胰腺癌研究的国家和国际研讨会、会议和会议。还有巴特拉医生 将协调该计划的所有活动，包括内部和外部咨询委员会，并将 担任内布拉斯加大学医学中心内其他适当学术单位的项目联络人 和外部实体。请求为一名专家工作人员提供核心支助，该专家将负责安排 所有内部和外部会议、预算监测和一般行政协助。核心A将 为所有三个研究项目和两个共享资源核心提供行政支持。Jane Meza博士 将对项目的总体统计分析和研究设计进行监督，并将领导一个团队 生物统计学家已被分配到个别项目和核心。另外巴布·古达博士会提供 生物信息学支持，包括数据挖掘和比较。这一点尤为重要，因为 项目1和2中提出的研究将从RNA测序分析中产生大量数据， 将需要使用强大的生物信息学工具来整合数据，并获得有意义的基本信息。 和临床推断。总之，科学和行政协调是成功的需要， 建议的计划，其中数据将来自研究项目和核心，ABC核心设备齐全 通过有效的管理和最先进的技术， 生物信息学方法。

ABSTRACT Dr. Surinder Batra will lead the Administrative and Bioinformatics Core (ABC) as a Program Director. Dr. Batra will provide oversight of the scientific and administrative activities of the program and chair the P01 Executive Committee which includes all research project leaders and shared core resource directors (Drs. Hollingsworth, Singh, Jain, and Thayer). Together, the team will foster communication and collaboration between the research projects and shared resource cores and monitor and assess progress. Dr. Batra will meet weekly with research project leaders and shared core resource directors, and he and his staff will serve as the editorial review/clearing house for all publications resulting from POI activities. The core will plan and coordinate regular seminars, which will include the project leaders, core directors, and investigators. These seminars will be a part of the monthly Pancreatic Cancer Program organized through other network programs in pancreatic cancer (SPORE, EDRN CVC, and TMEN). Core A will encourage, facilitate and coordinate the participation of PPG investigators in national and international workshops, conferences, and meetings on pancreatic cancer research. Also, Dr. Batra will coordinate all the activities of the Program including Internal and External Advisory Committees and will serve as the Program liaison with other appropriate academic units within University of Nebraska Medical Center and with outside entities. Core support is requested for a Staff Specialist who will be responsible for scheduling all internal and external meetings, budgetary monitoring, and general administrative assistance. Core A will provide administrative support for all three research projects and the two shared resource cores. Dr. Jane Meza will provide supervision for the overall statistical analysis and study design of the program and will lead a team of biostatisticians that have been assigned to individual projects and cores. Besides, Dr. Babu Guda will provide bioinformatics support including data mining and comparisons. This is particularly important because some of the studies proposed in project 1 and 2 will yield a large amount of data from RNA sequencing analysis which will require the employment of powerful bioinformatics tools to integrate the data and derive meaningful basic and clinical inferences. Altogether, the scientific and administrative coordination is needed for the success of the proposed Program where data will come from Research Projects and Cores, and the ABC core is well equipped to fulfill the administrative and scientific requirements databases through effective management and state-or-art Bioinformatics approaches.