UAB Predoctoral Training Grant in Translational and Molecular Sciences

这是一个新的博士前培训补助金申请在翻译和分子科学（TMS）在 亚拉巴马大学伯明翰分校（UAB）。目前，很少有博士毕业生进入劳动力市场， 充分的疾病病理生物学培训和翻译经验，以有效地翻译分子 推进临床实践。本提案满足了这一需求，我们的目标是提供培训 培养下一代博士生物医学科学家所需技能的环境， 将翻译目标纳入他们的研究，并为明天的劳动力做好准备。我们 最近的研究生教育经验表明，学生对翻译培训的需求有所增加。 research.对博士前学生进行有效的转化科学培训的一个主要挑战是需要 结合多学科和概念，从了解疾病机制， 了解研究结果如何在学术界或工业界转化，了解监管监督 程序和规则。我们提出了一个为期2年的计划（每年6名学生），学生在 他们的第二年开始。一个综合性的课程建议，涉及教学要素（即 包括了解疾病机制，药物发现和开发，转化研究 管理），职业和转化研究丰富活动（包括证书注册 计划在转化和分子科学，学术界和行业研讨会，CTSA的互动和 以团队为基础的练习，促进创新，创业精神和必要的技能和知识， 商业化发现）和有意义的临床/患者互动经验，后者将是 与学员的研究兴趣相联系。我们认为，为学生提供翻译研究方面的培训 在学生入学的早期，将培养技能，使他们能够将翻译思维纳入 他们的研究，并为未来劳动力的多样化需求做好准备。为了实现这一目标，我们必须 汇集了60名培训教师，拥有资金充足的实验室和独特的专业知识和经验， 解决基本的科学问题，重点是翻译和人类疾病。几 疾病领域，是UAB的常年优势代表，并将为学生提供广度， 不同的研究学科。这项建议强调了我们以前和正在进行的承诺，博士前 教育和我们的共同目标，为学生提供一个学习和发展技能的环境， 将需要在生物医学研究和其他科学相关的职业取得成功。

This is a new pre-doctoral training grant application in Translational and Molecular Sciences (TMS) at the University of Alabama at Birmingham (UAB). Currently, too few PhD graduates are entering the workforce with sufficient training in pathobiology of disease and translational experiences to effectively translate molecular advances into clinical practice. This proposal addresses this need with our goal being to provide a training environment that develops the necessary skills for the next generation of PhD biomedical scientists to incorporate translational objectives into their research and prepare them for the workforce of tomorrow. Our recent experiences in graduate education show increased demand from students for training in translational research. A major challenge in effective training in translational sciences for pre-doctoral students is the need to incorporate multiple disciplines and concepts ranging from understanding disease mechanisms, understanding of how findings may be translated in academia or industry, to understanding regulatory oversight procedures and rules. We propose a 2 year program (with 6 students per year) with students enrolling at the beginning of their second year. An integrative curriculum is proposed that involves didactic elements (that includes understanding disease mechanisms, drug discovery and development, translational research administration), career and translational research enrichment activities (including enrollment in a Certificate program in Translational and Molecular Sciences, academia and industry workshops, CTSA interactions and team based exercises that foster innovation, entrepreneurship and requisite skills and knowledge for commercializing discoveries) and meaningful clinical / patient interaction experiences, the latter of which will be linked with the trainees’ research interests. We feel that providing students with training in translational research early during a student’s matriculation will develop skills and enable them to incorporate translational thinking into their research and prepare them for the diverse requirements for the future workforce. To achieve this, we have assembled 60 training faculty with well-funded laboratories and a unique array of expertise and experience that address fundamental scientific problems with a strong emphasis on translation and human disease. Several disease areas that are perennial strengths of UAB are represented and will provide breadth for students in diverse research disciplines. This proposal underscores our previous and ongoing commitment to pre-doctoral education and our collective goal of providing an environment for students to learn and develop the skills they will require to be successful in the biomedical research and other science related occupations.