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中文摘要
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发展核心(核心B) 项目总结 发展核心是DC CFAR使命的驱动力,以加强我们的多机构努力,以 促进和支持有助于在华盛顿特区和其他地区结束艾滋病毒流行的研究 与政府和社区建立伙伴关系。核心由一支经验丰富的资深团队领导 自2010年CFAR成立以来的艾滋病毒研究人员:Michael Bukrinsky博士(GW,主任),Sylvia Silver (GW,联席董事)和Anthony Wu toh(胡,联席董事)。核心的具体目标是:1)促进 并支持与#年疫情有关的创新、合作和多学科的艾滋病毒研究 华盛顿特区通过飞行员奖、过渡调查员和小额赠款计划;2)领导 针对早期和过渡阶段艾滋病毒调查员的动态指导方案,重点是妇女 和代表性不足的少数群体;以及3)提供教育和网络活动,以促进 艾滋病毒研究中的多学科和跨机构合作。 自2010年以来,发展核心审查了165份试点奖项申请,并以280万美元资助了63份。引航员 从2010-2016年间发放的130万美元奖金中,美国国立卫生研究院新增拨款112万美元,占761% 投资回报。在所有华盛顿CFAR飞行员奖获得者中,56%是女性,23% 少数族裔的代表性不足。自2018年以来,核心审查了8份来自非艾滋病毒R01的申请- 资助过渡中的调查人员,资助两个20万美元,并已授予36个小额赠款6.8万美元 2010年。核心的指导、教育和培训计划通过提供 为华盛顿的艾滋病毒研究人员提供全面支持,包括个性化的核心服务、赠款 研讨会、指导研讨会、特定目标回顾、期刊俱乐部网络研讨会、网络机会和 全市范围的研究研讨会。
英文摘要
DEVELOPMENTAL CORE (CORE B) PROJECT SUMMARY The Developmental Core is the driving force of the DC CFAR mission to intensify our multi-institutional effort to promote and support research that contributes to ending the HIV epidemic in Washington, DC and beyond in partnership with government and community. The Core has been led by a highly experienced team of senior HIV researchers since the inception of the CFAR in 2010: Drs. Michael Bukrinsky (GW, Director), Sylvia Silver (GW, Co-Director) and Anthony Wutoh (HU, Co-Director). The Specific Aims of the Core are: 1) to promote and support innovative, collaborative and multidisciplinary HIV research that is pertinent to the epidemic in Washington, DC through the Pilot Awards, Transitioning Investigator and microgrants programs; 2) to lead a dynamic mentoring program for early stage and transitioning HIV investigators with an emphasis on women and underrepresented minorities; and 3) to provide educational and networking activities that promote multidisciplinary and cross-institutional collaboration in HIV research. Since 2010, the Developmental Core has reviewed 165 pilot award applications and funded 63 for $2.8M. Pilot awards granted from 2010-2016 for $1.3M have resulted in $11.2M in new NIH grants representing a 761% return on investment. Fifty-six percent of all DC CFAR pilot award recipients have been women and 23% have been underrepresented minorities. Since 2018, the Core has reviewed eight applications from non-HIV R01- funded transitioning investigators, funding two for $200,000, and has awarded 36 microgrants for $68K since 2010. The Core's mentoring, educational and training programs complement the awards program by providing comprehensive support to DC-based HIV researchers including individualized Core services, grantwriting workshops, mentoring workshops, specific aims reviews, journal club webinars, networking opportunities and citywide research seminars.
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Development of NLRP3 inhibitors for HIV-associated neuroinflammation
  • 批准号:
    10548568
  • 项目类别:
  • 资助金额:
    $21.2万
  • 财政年份:
    2022
  • 负责人:
    MICHAEL Ilya BUKRINSKY
  • 依托单位:
Trained immunity induced by Nef-containing extracellular vesicles
  • 批准号:
    10664031
  • 项目类别:
  • 资助金额:
    $20.19万
  • 财政年份:
    2022
  • 负责人:
    MICHAEL Ilya BUKRINSKY
  • 依托单位:
Trained immunity induced by Nef-containing extracellular vesicles
  • 批准号:
    10534002
  • 项目类别:
  • 资助金额:
    $24.23万
  • 财政年份:
    2022
  • 负责人:
    MICHAEL Ilya BUKRINSKY
  • 依托单位:
Development of NLRP3 inhibitors for HIV-associated neuroinflammation
  • 批准号:
    10650871
  • 项目类别:
  • 资助金额:
    $23.61万
  • 财政年份:
    2022
  • 负责人:
    MICHAEL Ilya BUKRINSKY
  • 依托单位: