Pilot Research Project Core

摘要-试点研究项目核心 我们正在建立一个试点研究项目核心（试点核心）作为我们中心的一部分，其总体目标是 建立一个具有技能和经验的调查人员管道，以进行高质量，尖端和/或 药物滥用和预防方面的快速反应研究。我们将通过三个目标来做到这一点：（1）管理 选择并监督执行实质上利用生物标志物的研究试点研究 （2）提高药物滥用和预防研究的质量， 学生和研究员，新的和早期阶段的研究人员，以及没有 药物生物标志物的专业知识;（3）支持药物滥用和预防研究， 美国各地的少数种族/族裔教师代表性不足。 为了实现目标1，试点核心将利用加州大学旧金山分校的资源分配计划（RAP）的赠款 征求、提交和审查。试点核心基金每年至少资助一个创新试点项目。为 目标2，试点核心将提供博士后研究员，新的和早期阶段的研究人员，并建立 不具备药物使用或药物生物标志物方面的专业知识的研究者在样本协助下 收集、研究设计和数据分析，沿着与开展药物研究相关的其他服务， 人类最后，对于目标3，试点核心将利用加州大学旧金山分校的学习早期职业成瘾和 多样性（LEAD）方案，以支持在代表性不足的人群中进行药物滥用和预防研究 来自美国各地大学的种族/少数民族教师通过分析化学支持他们的 牵头机构资助的项目。 这三个目标将推动药物滥用和预防研究领域， 试点研究，以刺激更大的项目，支持研究人员谁还没有经验或专业知识， 药物生物标志物，并支持培训代表性不足的种族/少数民族教师研究人员， 药物滥用和预防研究领域。

ABSTRACT- PILOT RESEARCH PROJECT CORE We are establishing a Pilot Research Project Core (Pilot Core) as part of our Center with the overarching goal of building a pipeline of investigators with the skills and experience to conduct high quality, cutting edge, and/or rapid response research in substance abuse and prevention. We will do so through three aims: (1) Administer the selection of and supervise the execution of research pilot studies that utilize biomarkers in substance abuse and prevention research; (2) Enhance the quality of substance abuse and prevention research among students and fellows, new and early stage investigators, and established investigators who do not have expertise in drug biomarkers; and (3) Support substance abuse and prevention research among underrepresented racial/ethnic minority faculty across the United States. To accomplish Aim 1, the Pilot Core will utilize UCSF's Resource Allocation Program (RAP) for grant solicitation, submission and review. The Pilot Core will fund at least one innovative pilot project annually. For Aim 2, the Pilot Core will provide postdoctoral fellows, new and early stage investigators, and established investigators who do not have expertise in substance use or drug biomarkers with assistance on sample collection, study design, and data analysis, along with other services related to conducting drug studies in humans. Finally, for Aims 3, the Pilot Core will leverage UCSF's Learning for Early Careers in Addiction & Diversity (LEAD) Program to support substance abuse and prevention research among underrepresented racial/ethnic minority faculty from universities across the U.S. through analytical chemistry support on their LEAD-funded projects. These three aims will advance the field of substance abuse and prevention research by facilitating the conduct of pilot studies to spur larger projects, supporting researchers who do not yet have experience or expertise in drug biomarkers, and supporting the training of underrepresented racial/ethnic minority faculty researchers in the field of substance abuse and prevention research.