Pilot Research Project Core

摘要-先导研究项目核心 我们正在建立一个试点研究项目核心(试点核心)，作为我们中心的一部分，总体目标是 建立一支拥有技能和经验的调查人员渠道，以进行高质量、尖端和/或 药物滥用和预防方面的快速反应研究。我们将通过三个目标来实现这一目标：(1)管理 选择和监督在实质上使用生物标志物的研究先导研究的执行 滥用和预防研究；(2)提高药物滥用和预防研究的质量 学生和研究员，新的和早期的调查人员，以及没有 药物生物标记物方面的专门知识；及(3)支持药物滥用和预防研究 在全美，种族/少数族裔教职员工的代表性不足。 为了实现目标1，试点核心将利用加州大学旧金山分校的资源分配计划(RAP)进行赠款 征集、提交和审查。试点核心每年将为至少一个创新试点项目提供资金。为 目标2，试点核心将提供博士后研究员、新的和早期的研究人员，并建立 对物质使用或药物生物标记物没有专业知识的调查人员，并在样本方面提供协助 收集、研究设计和数据分析，以及与开展药物研究有关的其他服务 人类。最后，对于AIMS 3，试点核心将利用加州大学旧金山分校在成瘾和早期职业生涯中的学习。 支持代表性不足的药物滥用和预防研究的多样性(牵头)计划 来自美国各地大学的种族/少数民族教师通过分析化学支持他们的 牵头资助的项目。 这三个目标将推动药物滥用和预防研究领域的开展 的试点研究，以刺激更大的项目，支持那些还没有经验或专业知识的研究人员 药物生物标志物，并支持培训代表不足的种族/少数族裔教职研究人员 药物滥用和预防研究领域。

ABSTRACT- PILOT RESEARCH PROJECT CORE We are establishing a Pilot Research Project Core (Pilot Core) as part of our Center with the overarching goal of building a pipeline of investigators with the skills and experience to conduct high quality, cutting edge, and/or rapid response research in substance abuse and prevention. We will do so through three aims: (1) Administer the selection of and supervise the execution of research pilot studies that utilize biomarkers in substance abuse and prevention research; (2) Enhance the quality of substance abuse and prevention research among students and fellows, new and early stage investigators, and established investigators who do not have expertise in drug biomarkers; and (3) Support substance abuse and prevention research among underrepresented racial/ethnic minority faculty across the United States. To accomplish Aim 1, the Pilot Core will utilize UCSF's Resource Allocation Program (RAP) for grant solicitation, submission and review. The Pilot Core will fund at least one innovative pilot project annually. For Aim 2, the Pilot Core will provide postdoctoral fellows, new and early stage investigators, and established investigators who do not have expertise in substance use or drug biomarkers with assistance on sample collection, study design, and data analysis, along with other services related to conducting drug studies in humans. Finally, for Aims 3, the Pilot Core will leverage UCSF's Learning for Early Careers in Addiction & Diversity (LEAD) Program to support substance abuse and prevention research among underrepresented racial/ethnic minority faculty from universities across the U.S. through analytical chemistry support on their LEAD-funded projects. These three aims will advance the field of substance abuse and prevention research by facilitating the conduct of pilot studies to spur larger projects, supporting researchers who do not yet have experience or expertise in drug biomarkers, and supporting the training of underrepresented racial/ethnic minority faculty researchers in the field of substance abuse and prevention research.