The University of Rochester Clinical and Translational Science Award Hub

联系PD/PI：Zand，马丁·S 核心O：总体--项目摘要/摘要 临床与翻译科学研究所(UR CTSI)是罗切斯特大学的研究引擎 医疗中心。UR CTSI促进了整个大学的研究，建立了强大的翻译 研究生态系统。在接下来的五年里，UR CTSI将把重点放在“无墙的翻译研究”上， 超越机构的物理和虚拟限制。我们将加快翻译服务的整合 使用学习健康系统进行研究。我们将扩大我们的创新传播方式和 实施(D&I)研究包括：一个新的专门的D&I KL2学者职位，一个健康-公平 有重点的传播和实施可选功能；以及有重点的协作试点方案 特别是在学习卫生系统内的D&I项目上。我们将开发和传播小说 教育材料和方法。我们将创建一个无缝转换的研究数据生态系统 通过链接我们的研究和临床数据仓库，集成翻译范围内的数据。我们 将实施ACT/SHARINE队列发现软件，并广泛使用健康数据中心 (CD2H)工具、本体和工作组。我们将在试点项目中扩大教育力度，以 实现翻译研究数据和分析方面的卓越。我们将加强翻译研究 各利益攸关方在地方和国家层面的协作。我们将继续我们的 与CTSA协调中心的广泛参与。我们将把我们成功的计划扩展到 以社区为基础的参与性研究，促进与社区成员组成多学科团队。 我们将扩大我们在地方和全国的合作。我们将教育下一代翻译 科学团队领导者，扩展我们的方法以确保在协作、技术、 以及加快将高影响力研究转化为临床应用所需的监管技能。我们 将开发和传播新的教育材料、研究人员支持和方法。我们将催化 制定、实施和传播促进 通过方法推进CTSA联盟的地方和全国翻译研究 远程数据和样本收集；在监管支持和行业支持下加快基础和早期研究 赞助；以及用于快速试验评估、谈判和批准的计划。我们将加强我们的参与者 和临床交互功能，以适应远程研究访问以及远程数据和样本捕获 方法：研究方法。我们将利用我们现有的优势来实施和管理多个地点的研究。 第172页 项目摘要/摘要 联系PD/PI：Zand，马丁·S 核心O.总体而言-

Contact PD/PI: Zand, Martin S CORE O: OVERALL – PROJECT SUMMARY/ABSTRACT The Clinical and Translational Science Institute (UR CTSI) is the research engine of the University of Rochester Medical Center. The UR CTSI has catalyzed research throughout the University, building a robust translational research ecosystem. During the next five years, the UR CTSI will focus on “translational research without walls,” moving beyond the physical and virtual confines of institutions. We will accelerate integration of translational research with the Learning Health System. We will expand our innovative approaches to dissemination and implementation (D&I) research including: a new and dedicated D&I KL2 scholar position, a Health-Equity Focused Dissemination and Implementation Optional Function; and a collaborative pilot program focused specifically on D&I projects within the Learning Health System. We will develop and disseminate novel educational materials and methods. We will create a translational research data ecosystem that seamlessly integrates data across the translational spectrum by linking our research and clinical data warehouses. We will implement the ACT/SHRINE cohort discovery software and make extensive use of Center for Data to Health (CD2H) tools, ontologies and working groups. We will expand education efforts across our pilot programs to achieve translational research data and analytic excellence. We will enhance translational research collaborations at the local and national levels across the spectrum of stakeholders. We will continue our extensive participation with the CTSA Coordinating Centers. We will extend our successful program in community-based participatory research, facilitating multidisciplinary team formation with community members. We will expand our local and national collaborations. We will educate the next generation of translational science workforce leaders, expanding our approaches to ensure competence in the collaborative, technical, and regulatory skills necessary to accelerate the translation of high impact research to clinical applications. We will develop and disseminate novel educational materials, investigator support, and methods. We will catalyze the development, implementation and dissemination of methods and processes that advance translational research locally and nationally across the CTSA Consortium through methods to advance remote data and sample collection; speeding basic and early stage research with regulatory support and industry sponsorship; and programs for rapid trial evaluation, negotiation, and approval. We will enhance our Participant and Clinical Interactions Function to accommodate teleresearch visits and remote data and sample capture methods. We will employ our existing strengths to implement and manage multi-site research studies. Page 172 Project Summary/Abstract Contact PD/PI: Zand, Martin S CORE O. OVERALL –