Research Training Program in Cardiovascular Surgery

摘要 心血管疾病及其并发症是美国死亡和残疾的主要原因 各州。外科心血管疾病对健康的影响产生了对外科研究的强烈需求。 不幸的是，心血管外科培训项目的毕业生面临着重新建立 寻找职业。利用我们在德克萨斯医疗中心的地位，德克萨斯医疗中心是全球最大的医疗综合体 在世界范围内，我们提出了心血管外科研究的博士后培训计划，将：(1)增加 进入心血管外科研究职业的医学博士和博士人才库，以及(2)为我们的学员提供 具备在心血管研究中取得成功和多产所必需的技能。我们建议实现 这些目标通过每年接收两名实习生(MD外科实习医生或博士)进入三个培训轨道， 每两年：生物工程和生物设计，基础和转化研究，以及临床和 结果研究。学员可以寻求不同的研究职业培训机会-从质量- 积极的以患者为中心的结果研究到心肌细胞再生的分子探索--但总的来说 案例重点是解决与心血管外科医生相关的临床问题。为了提供一种 在一系列培训机会中，我们从莱斯贝勒医学院招募了20名导师 大学和休斯顿大学。[我们的导师总共有超过1620万美元的研究资金 并在过去10年中培训了240多名博士后研究员。]在三个训练赛道中，20个 导师根据他们的专业知识和现有的专业知识被分成几个特定的主题，如“主动脉疾病”。 合作关系。每个课程都允许学员完成一个学位，如临床再培训硕士学位。 通过德克萨斯医学中心建立的研究生课程进行搜索。我们的节目负责人是托德 罗森加特，医学博士，BCM迈克尔·E·德巴基外科主任；联席主任斯科特·勒- 麦尔，医学博士，研究副主席，芭芭拉·特劳特纳，医学博士，临床研究主任。我们的领头羊- 职业资格将由一个执行指导委员会和五个小组委员会提供支持：选拔、课程、 个人发展、项目评估和教师评估。执行指导委员会将 还接受外部咨询委员会的意见，该委员会由三名外科医生组成，他们都指导了 T32培训计划。[我们竞争激烈的申请者群包括2,587个医学博士或综合学位申请- 我们的普通外科住院医师研究轨道和152名博士后研究申请者到我们的 BCM、莱斯大学和休斯顿大学的导师系(从2017年开始)。]按顺序 为了确保学员的多样性，我们得到了BCM机构多样性办公室的支持 并被纳入，以在实习面试日提供帮助并参加我们的遴选委员会。带到- 此外，我们相信，这些资格证书为我们的计划提供了一个理想的机会，以增强 高素质的医学博士和博士，为心血管外科研究领域的高影响力做出贡献。

ABSTRACT Cardiovascular diseases and their complications are leading causes of death and disability in the United States. The health implications of surgical cardiovascular disease create a strong need for surgical research. Unfortunately, graduates of cardiovascular surgery training programs face steep challenges to establishing re- search careers. Taking advantage of our position in the Texas Medical Center, the largest medical complex in the world, we propose atpostdoctoral training program in cardiovascular surgical research that will: (1) increase the pool of MDs and PhDs who enter cardiovascular surgical research careers, and (2) provide our trainees with the skills necessary to be successful and productive in cardiovascular research. We propose to achieve these goals through accepting two trainees per year (MD surgery residents or PhDs) into three training tracks, each two years in duration: bioengineering and biodesign, basic and translational research, and clinical and outcomes research. Trainees can pursue diverse research career training opportunities—ranging from qualita- tive patient-centered outcomes research to a molecular exploration of cardiac myocyte regeneration—yet in all cases the focus is on addressing a clinical problem relevant to cardiovascular surgeons. In order to provide a range of training opportunities, we have recruited 20 mentors from Baylor College of Medicine (BCM), Rice University, and the University of Houston. [Our mentors collectively have over $16.2 million in research funding and have trained over 240 postdoctoral fellows over the past 10 years.] Within the three training tracks, the 20 mentors are grouped into specific themes, such as “aortic disease,” based on their expertise and existing col- laborative relationships. Each track allows trainees to complete a degree, such as a Master in Clinical Re- search, through an established graduate program in the Texas Medical Center. Our program director is Todd Rosengart, MD, Chair of the Michael E. DeBakey Department of Surgery at BCM; co-directors are Scott Le- Maire, MD, Vice Chair for Research, and Barbara Trautner, MD, PhD, Director of Clinical Research. Our lead- ership will be supported by an Executive Steering Committee and five subcommittees: Selection, Curriculum, Individual Development, Program Evaluation, and Faculty Evaluation. The Executive Steering Committee will also receive input from an External Advisory Committee composed of three surgeons who have all directed T32 training programs. [Our highly competitive applicant pool includes 2,587 MD or combined degree appli- cants to our general surgery residency research track and 152 PhD postdoctoral research applicants to our mentors' departments at BCM, Rice University, and the University of Houston (numbers from 2017).] In order to ensure diversity among our trainees, we have enlisted the support of the BCM Office of Institutional Diversity and Inclusion to help during residency interview days and to participate in our Selection Committee. Taken to- gether, we believe these qualifications provide an ideal opportunity for our program to enhance the pool of highly qualified MDs and PhDs contributing to the high-impact arena of research in cardiovascular surgery.