ASD3MAP: Amorphous Solid Dispersion Digital Design and Manufacturing Platform for rapid and resource-efficient development of bioavailable medicines

_*ASD3MAP：无定形固体分散体数字化设计和制造平台，用于快速和资源有效地开发生物利用度药物。**_ MESOX有限公司（牵头）与阿斯顿大学（合作伙伴）合作，提出了一个为期18个月的项目，重点是通过整合市场上的材料科学和模拟工具来完善联盟的分子动力学模型，为无定形固体分散体（ASD）提供先进的计算机配方开发平台。此外，我们将把生成的建模数据与热力学和新的计算流体动力学（CFD）模型相结合，以预测cGMP生产规模扩大对制剂的影响。

_**ASD3MAP: Amorphous Solid Dispersion Digital Design and Manufacturing Platform for rapid and resource-efficient development of bioavailable medicines.**_MESOX Ltd (Lead), in collaboration with Aston University (Partner), propose an 18-month project focussing on the refinement of the Consortium's molecular dynamics models through the integration of at market material science and simulation tools to deliver an advanced in-silico formulation development platform for amorphous solid dispersions (ASDs). Furthermore, we will integrate the generated modelling data with thermodynamics and novel computational fluid dynamics (CFD) models to predict the impact of cGMP manufacturing scale-up on the formulation.