Core C: Cellular Purification and Analysis Core MSU COBRE Phase II

项目摘要：核心C 获取和获取/操作/维护现代研究仪器是取得成功的关键 生物医学研究人员。具体地说，在分离和纯化特定细胞方面的技术和专业知识 这些细胞的类型以及成像和分析对于病原体-宿主的Cobre第二阶段工作至关重要 互动。密西西比州立大学(MSU)的研究基础设施是这样的，我们装备精良 以满足科布雷第二阶段牵头调查员项目的需求。Cobre第二阶段核心C，细胞纯化 分析公司有一个成功的模式，可以提供一种管理机制来确保访问 仪器和专业知识，以加强现有基础设施、稳定性和技术的可持续性 科布雷项目所需的，并提供调查人员所需的技术和分析支持 需要在这部科布雷中取得成功。这一努力利用了富有成效的服务中心的历史 一个成功的商业模式，它导致了一个多产、高效和成功的Cobre阶段I目标 核心C的核心是继续将现有设备和人员整合到Cobre中并在其基础上进行建设 氛围不仅使科布雷研究人员的访问更有效率，而且还刺激了生物医学 密歇根州立大学的总体研究。这将通过核心C的三个具体目标来实现：1)提供 确保Cobre调查人员获得蜂窝设备和专业知识的管理机制 纯化和分析。2)增强现有基础设施、稳定性和细胞纯化的可持续性 科布雷项目所需的分析技术。3)提供所需的技术和分析支持 科布雷研究人员希望在生物医学研究方面取得成功。完成这些具体目标将 使个别Cobre调查人员能够取得成功，增强现有的协作基础设施 生物医学研究和教学，并为生物医学研究成功做出重大贡献，网址为 密歇根州立大学。总体而言，Cobre第二阶段领导团队、行政核心A、技术核心B和C以及 牵头调查人员，在大学支持、基础设施和协作精神的支持下，确保继续 发展和壮大多学科专题研究的重点和方案方面的成功 科布雷在创建充满活力的可持续生物医学研究计划方面发挥了重要作用。

Project Summary: Core C Access to and acquisition/operation/maintenance of modern research instrumentation is critical to the success of biomedical researchers. Specifically, technology and expertise in separation and purification of particular cell types as well as imaging and analysis of those cells is critical for this COBRE Phase II effort in Pathogen-Host Interactions. The research infrastructure at Mississippi State University (MSU) is such that we are well equipped to meet the needs of COBRE Phase II Lead Investigator projects. COBRE Phase II Core C, Cellular Purification and Analysis has a successful model to provide an administrative mechanism to ensure access to instrumentation and expertise, to enhance existing infrastructure, stability, and sustainability of technologies required for COBRE projects, and to provide technologies and analytical support required by investigators needed to be successful in this COBRE. This effort takes advantage of a productive service center history with a successful business model, which led to a productive, efficient, and successful COBRE Phase I. The Objective of Core C is to continue integrating and building on existing equipment and personnel into the COBRE atmosphere not only to make access more efficient for COBRE Investigators but also to stimulate biomedical research at MSU in general. This will be accomplished through three Specific Aims of Core C: 1) Provide the administrative mechanism to ensure COBRE Investigators access to instrumentation and expertise for cellular purification and analysis. 2) Enhance existing infrastructure, stability, and sustainability of cell purification and analysis technologies required for COBRE projects. 3) Provide technologies and analytical support required by COBRE Investigators to be successful in biomedical research efforts. Completion of these Specific Aims will enable the success of individual COBRE Investigators, enhance the existing collaborative infrastructure for biomedical research and teaching, and contribute significantly to the biomedical research success portfolio at MSU. Collectively, the COBRE Phase II Leadership Team, Administrative Core A, technical Cores B and C, and Lead Investigators, with University support, infrastructure and a collaborative spirit ensures the continued development and growth of the thematic multidisciplinary research focus of and programmatic success of the COBRE in creating a vibrant sustainable biomedical research program.