Core C: Cellular Purification and Analysis Core MSU COBRE Phase II

项目概要：核心C 现代研究仪器的获取/操作/维护是成功的关键 生物医学研究人员。具体而言，在分离和纯化特定细胞方面的技术和专业知识 这些细胞的类型以及成像和分析对于COBRE在病原体-宿主研究中的第二阶段工作至关重要 交互.密西西比州立大学（MSU）的研究基础设施是这样的，我们装备精良 满足COBRE第二阶段首席研究员项目的需求。COBRE II期核心C，细胞纯化 在提供一种行政机制以确保获得 仪器和专业知识，以加强现有的基础设施，稳定性和技术的可持续性 COBRE项目所需的技术和分析支持，并提供调查人员所需的技术和分析支持 必须在眼镜蛇行动中取得成功这项工作利用了生产服务中心的历史， 一个成功的商业模式，导致了一个生产力，效率和成功的COBRE第一阶段。客观 核心C的核心是继续将现有的设备和人员集成到COBRE中，并在此基础上进行建设 不仅使COBRE调查人员的访问更有效，而且还促进生物医学 一般来说，MSU的研究。这将通过核心C的三个具体目标来实现：1）提供 行政机制，以确保COBRE调查人员能够使用仪器和专业知识， 纯化和分析。2)加强现有的基础设施、稳定性和细胞纯化的可持续性， COBRE项目所需的分析技术。3)提供所需的技术和分析支持 COBRE研究人员在生物医学研究工作中取得成功。这些具体目标的实现将 使个别COBRE调查员取得成功，增强现有的协作基础设施， 生物医学研究和教学，并作出重大贡献的生物医学研究的成功组合在 密歇根州立大学。总体而言，COBRE第二阶段领导团队、行政核心A、技术核心B和C，以及 首席研究员，与大学的支持，基础设施和合作精神，确保持续 发展和增长的专题多学科研究的重点和方案的成功， COBRE致力于创建一个充满活力的可持续生物医学研究计划。

Project Summary: Core C Access to and acquisition/operation/maintenance of modern research instrumentation is critical to the success of biomedical researchers. Specifically, technology and expertise in separation and purification of particular cell types as well as imaging and analysis of those cells is critical for this COBRE Phase II effort in Pathogen-Host Interactions. The research infrastructure at Mississippi State University (MSU) is such that we are well equipped to meet the needs of COBRE Phase II Lead Investigator projects. COBRE Phase II Core C, Cellular Purification and Analysis has a successful model to provide an administrative mechanism to ensure access to instrumentation and expertise, to enhance existing infrastructure, stability, and sustainability of technologies required for COBRE projects, and to provide technologies and analytical support required by investigators needed to be successful in this COBRE. This effort takes advantage of a productive service center history with a successful business model, which led to a productive, efficient, and successful COBRE Phase I. The Objective of Core C is to continue integrating and building on existing equipment and personnel into the COBRE atmosphere not only to make access more efficient for COBRE Investigators but also to stimulate biomedical research at MSU in general. This will be accomplished through three Specific Aims of Core C: 1) Provide the administrative mechanism to ensure COBRE Investigators access to instrumentation and expertise for cellular purification and analysis. 2) Enhance existing infrastructure, stability, and sustainability of cell purification and analysis technologies required for COBRE projects. 3) Provide technologies and analytical support required by COBRE Investigators to be successful in biomedical research efforts. Completion of these Specific Aims will enable the success of individual COBRE Investigators, enhance the existing collaborative infrastructure for biomedical research and teaching, and contribute significantly to the biomedical research success portfolio at MSU. Collectively, the COBRE Phase II Leadership Team, Administrative Core A, technical Cores B and C, and Lead Investigators, with University support, infrastructure and a collaborative spirit ensures the continued development and growth of the thematic multidisciplinary research focus of and programmatic success of the COBRE in creating a vibrant sustainable biomedical research program.