The second phase of NIH Common Fund 4D Nucleome Network Organizational Hub

美国国立卫生研究院共同基金4D核组网络组织中心二期 摘要 4DN计划的第二阶段需要一个有效的组织中心，以协同以下活动 所有资助的团队和集成的研究产品。在此基础上提出了4DN组织枢纽 要：(1)协调和整合所有资助项目的努力，(2)建立高效的联合体基础设施 作为协作努力的中心，以及(3)提供4DN网络门户作为中心资源 访问所有4DN-Network生成的工具、策略、指南、协议、试剂、细胞系和 作为外联活动的中心枢纽。我们的主要成果是：(1)组织结构由 具有明确的报告链的指导委员会和问题解决工作组，以实现有效的 沟通和决策过程，建立共同组织者和时间表，澄清行动项目，以及 确保行动项目的执行；(2)4DNWeb门户(https://www.4dnucleome.org/)，始终是 最新的社区范围资源和所有数据、协议、试剂、资源和 方法；(3)4DN内部维基，为所有团队、中心和工作组提供的中央组织资源，以 记录内部进度。(4)4DN年度会议，包括2020年冬季的“启动”会议和 随后的年会和4DN-ASCB(美国细胞生物学学会)卫星会议；(5)4DN 在Keystone研讨会和美国人类遗传学学会(ASHG)会议上举办外联讲习班，以及 在4DNYouTube频道。

The second phase of NIH Common Fund 4D Nucleome Network Organizational Hub Abstract The second phase of the 4DN program requires an efficient organizational center to synergize the activities of all the funded teams and integrate the research products. Accordingly, the 4DN Organizational Hub is proposed to: (1) coordinate and integrate the efforts of all the funded projects, (2) build an efficient consortium infrastructure to serve as a center for the collaborative efforts, and (3) provide the 4DN web portal as a central resource gateway to access all the 4DN-Network generated tools, policies, guidelines, protocols, reagents, cell lines, and as a central hub for the outreach activities. Our major deliverables are: (1) an organizational structure composed of a steering committee and problem-solving working groups with a clear report chain to enable effective communications and decision-making processes, establish co-organizers and schedule, clarify action items, and ensure execution of the action items; (2) 4DN Web Portal (https://www.4dnucleome.org/), which is the always up-to-date community-wide resource and point of access for all data, protocols, reagents, resources, and methods; (3) 4DN internal wiki, the central organized resource for all teams, centers, and working groups to document internal progresses. (4) 4DN annual meetings, including the "kick-off" meeting in winter 2020 and the subsequent annual meetings and 4DN-ASCB (American Society of Cell Biology) satellite meetings; (5) 4DN outreach workshops at Keystone symposia and American Society of Human Genetics (ASHG) meetings, and on 4DN YouTube channel.