Center for Advancing COVID-19 health Equity Research

项目摘要 少数人参加临床试验是必不可少的，因为它使科学家能够评估安全性， 医疗产品的有效性，包括药物、疫苗和这些产品中的器械 基因/种族多样化的人群。尽管如此，少数参与临床试验的人 仍然很低。这项拨款提案的总体目标是调查低收入的可能原因。 COVID-19/COVID-19变异株临床试验中的种族和少数民族人群入组 并确定解决方案，以克服低入学率。多年来，药学院 和药物科学，公共卫生研究所已制定了强有力的合作 与东北佛罗里达医学会、威廉古恩的 医学会，特纳联盟咨询公司和东海岸研究所。在此提出的 调查，我们将与这些组织合作，重点放在三个具体目标1）确定 当地社区的主要差距，导致种族和民族入学率低， COVID-19临床试验中的少数群体，2）开发，试点和评估社区- 基于有针对性的战略，积极提高少数民族和少数民族的入学率 当地COVID-19临床试验中的人群; 3）为以下人员提供临床研究Fastrack培训 三个地理区域（杰克逊维尔，坦帕， Tallahassee，FL）。调查人员将对社区进行定性访谈， 医疗保健提供者和社区领导人讨论战略/教育方法，以增加 招募少数群体参加临床试验，并确定健康顾问/大使， 为社区举办以COVID-19临床试验为重点的教育课程。一个网站 将沿着开发包含临床试验信息和常见问题的 网站信息的广告牌。 这项拟议研究的预期成果是确定 种族和少数民族人口在COVID中入学率低的可能原因- 19/COVID-19变异株临床试验。我们的主要目标是开发一个可行的模型， 少数群体对COVID-19/COVID-19变异临床研究试验的认识和参与。

PROJECT SUMMARY Minority enrollment in clinical trials is essential as it allows scientists to evaluate the safety and efficacy of medical products, including medications, vaccines, and devices within these genetically/ethnically diverse populations. Despite this, minority participation in clinical trials remains low. The overall goal of this grant proposal is to investigate possible causes of low enrollment of racial and ethnic minority populations in COVID-19/COVID-19 variant clinical trials and determine solutions to overcome low enrollment. Over the years, the College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health has developed strong collaborative relationships with organizations such as Northeast Florida Medical Society, William Gunn’s Medical Society, Turner Alliance Consulting, and East Coast Research Institute. In this proposed investigation, we will partner with these organizations to focus on three specific aims 1) Identify the major gaps in the local communities that contribute to the low enrollment of racial and ethnic minority populations in COVID-19 clinical trials, 2) Develop, pilot, and evaluate a community- based targeted strategy to actively improve the enrollment of the racial and ethnic minority population in local COVID-19 clinical trials and 3) Provide Clinical Research Fastrack training for 30 minority healthcare providers and workers in three geographic areas (Jacksonville, Tampa, Tallahassee, FL). The investigators will conduct qualitative interviews with the community, healthcare providers, and community leaders to discuss strategies/education methods to increase enrollment for minority populations in clinical trials and identify health advisors/ambassadors to conduct educational sessions for the community focusing on COVID-19 clinical trials. A website containing clinical trial information and frequently asked questions will be developed along with billboards with website information. The expected outcome of this proposed study is to identify the possible causes of low enrollment of racial and ethnic minority populations in COVID- 19/COVID-19 variant clinical trials. Our major goal is to develop a workable model to increase awareness and participation of minorities in COVID-19/COVID-19 variant clinical research trials.