Innovative NextGen pig breeding using DNA sequence data

该项目通过大幅提高猪的基因组选择效率来解决粮食安全和可持续性问题。具体来说，我们将基于大量序列数据的收集和利用，开发一项名为“下一代育种”（NextGen Breeding）的新技术，这将使我们能够大大加快猪群遗传改良的速度。该项目涉及两个世界级的英国合作伙伴，PIC （Genus plc的一部分），世界领先的生猪养殖公司和罗斯林研究所（RI），世界领先的基因组学和数量遗传学应用于农场动物育种的研究中心。该项目需要以前所未有的规模对样本进行全基因组测序，尽管我们的创新方法大大降低了传统范例的成本，但风险和成本仍然相当大。

This Project addresses food security and sustainability by substantially increasing the efficiency of genomic selection of pigs. Specifically we will develop a new technology we call NextGen Breeding, based on the collection and utilization of very large quantities of sequence data, which will enable us to dramatically accelerate the rate of genetic improvement in our pig populations. The project involves collaboration between two world class UK partners, PIC (part of Genus plc), the world’s leading pig breeding company and The Roslin Institute (RI), the world’s leading research centre in the application of genomics and quantitative genetics to farm animal breeding. The project requires whole genome sequencing of samples on an unprecedented scale and even though our innovative approach dramatically reduces the costs over the conventional paradigm, the risk and costs are still considerable.