Understanding platinum dissolution in biomedical stimulating electrodes

铂金是人工耳蜗等神经刺激器电极的主要材料。铂电极在植入过程中会发生溶解，影响其功能。控制这一溶解过程的机制是复杂的，仍然没有完全理解。本研究旨在了解影响铂在电极中溶解的化学、电学和生物学因素。该公司还将开发新的3D模型来模拟人体状况，以便对电极进行更快速的测试。所产生的新知识将提高铂溶解预测的准确性，开发最小化溶解的新方法，并有助于减少对动物实验的需求。

Platinum is the main material used in electrodes for neurostimulators like the cochlear implant. Platinum electrodes can experience dissolution during implantation, which can impact on their function. The mechanisms governing this dissolution process are complex and still not fully understood. This research aims to understand the chemical, electrical and biological factors that impact on platinum dissolution in electrodes. It will also develop new 3D models to simulate conditions in the human body for more rapid testing of electrodes. The new knowledge generated will improve the accuracy of predictions of platinum dissolution, develop new approaches for minimising dissolution, and contribute to reducing need for animal experimentation.