Novel methods to identify and isolate bio-active iminosugars for rumen manipulation.

亚胺糖是一类广泛存在的植物和微生物化合物，由于它们能够与肠道内的酶和微生物相互作用，因此作为治疗剂引起了人们的兴趣。他们有许多有益于健康的活动，但由于难以辨认和隔离，大多数人仍未得到调查。在这里，我们专注于从植物原料和食物垃圾中鉴定和分离新的生物活性亚胺糖。我们希望在反刍动物饲料行业找到这些化合物的市场，在那里它们可能有助于取代动物饲料中抗生素的使用，以开发提高国内供应的反刍动物肉类和牛奶的生产效率和可持续性的产品，减少供应链中的碳足迹，并改善供人类食用的肉类和牛奶的营养价值。

The iminosugars are a widespread group of plant and microbial compounds that are attracting interest as therapeutic agents due to their ability to interact with enzymes and microbes within the gut. They have many activities beneficial to health but due to difficulties with their identification and isolation most remain un-investigated. Here we focus on the identification and isolation of novel bioactive iminosugars from plant materials and food waste streams. We hope to find a market for these compounds in the ruminant feed sector where they may help replace the use of antibiotics in the animals diet to develop products that increase the production efficiency and sustainability of domestically supplied ruminant meat and milk for food, reducing the carbon footprint in the supply chain and improving the nutritional value of meat and milk for human consumption.