Scale-up and commercial evaluation of the manufacture of bio-based FDCA from HMF

围绕使用化石燃料和粮食作物的环境和社会问题使木质纤维素成为具有挑战性但令人信服的高价值化学品的目标来源。由Biome、过程创新中心（CPI）和利兹大学、利物浦大学和华威大学进行的先前和正在进行的IB催化剂研究已经证明了从木质纤维素到聚酯前体的生物过程的可行性。该项目将寻求开发一个连续的，中试规模的酶工艺，以生产高纯度的聚酯前驱物，并将其转化为一套高功能的聚酯。这项工作将由Biome技术有限公司、利物浦大学和利兹大学组成的一个财团承担。我们相信该项目有潜力提升英国在先进生物基材料领域的知识和商业地位。

The environmental and social concerns surrounding the use of fossil fuels and food crops make lignocellulose a challenging but compelling target source of high value chemicals. Previous and ongoing IB Catalyst studies undertaken by Biome, the Centre for Process Innovation (CPI) and the Universities of Leeds, Liverpool and Warwick have demonstrated the feasibility of bioprocesses from lignocellulose to polyester pre-cursors. This project will seek to develop a continuous, pilot-scale enzymic process to produce a high purity polyester pre-cursor and convert it into a suite of highly functional polyesters. The work will be undertaken by a consortium of Biome Technologies Ltd and the Universities of Liverpool and Leeds. We believe that the project has the potential to advance the UK’s knowledge and commercial position in the field of advanced bio-based materials.