A ‘healthy’ processed food to normalise and maintain blood sugar levels in individuals at risk of Type-II Diabetes

该项目将确保饮食干预的关键数据，以降低被定义为“糖尿病前期”的人的空腹血糖（FBG）水平。这种性质的简单饮食解决方案有可能对II型糖尿病（T2D）的发病率产生显著影响，II型糖尿病是英国和全世界的主要且日益严重的问题：据估计，英国有1500万糖尿病前期患者，400万患有T2D，全球有超过10亿糖尿病前期患者和3.7亿糖尿病患者。仅糖尿病处方每年就花费NHS超过10亿英镑。因此，该项目解决了一个非常重要的公共卫生问题，并且有巨大且不断增长的市场机会。使用我们专有的汤产品进行的为期两年的饮食和前列腺癌研究的数据显示，个体的血糖水平低于正常水平，并保持在与健康相关的水平，并在试验期间保持在较低水平。这种效果是通过每周只喝一份300毫升的汤来实现的，没有其他饮食或生活方式的改变。降低血糖不是这项研究的主要终点，需要进行更大规模的研究，特别关注我们的食品对血糖的影响。Smarter Food Company（TSFC）已经成立，以开发这项技术，并将有助于血糖管理的食品推向市场。TSFC正在寻求UKI2S加速器资金，并与私人投资相匹配，以进行一项关键规模的人体试验，并设计，以测试一份汤将糖尿病前期个体的血糖降低到“健康”水平的假设。这种汤是由一种独特的、专有的西兰花制成的，这种西兰花天然培育，含有非常高浓度的萝卜硫苷（VHG）。这种汤将用于验证最初的发现，并确认萝卜硫苷在提供所需效果中的作用。试验的成功结果将带动大量私人投资，将这种产品以及未来的产品推向市场。这些食品将销售给糖尿病前期患者，参与筛查，监测和治疗T2D的医疗保健专业人员，糖尿病慈善机构和其他相关非政府组织，健康意识和担忧，并获得批准的欧洲食品标准局（EFSA）健康声明，以及其他市场的等效产品。这些产品将通过主要食品零售商和网上直销销售。

This project will secure critical data for a dietary intervention to reduce fasting blood glucose (FBG) levels in people who are defined as being 'pre-diabetic'. A simple dietary solution of this nature has the potential to have a significant impact on the incidence of type-II diabetes (T2D), a major and growing problem in UK and throughout the world: it is estimated that there are 15m pre-diabetic people in the UK and 4m with T2D and globally over 1bn pre- diabetic and 370m diabetic. Diabetes prescriptions alone cost the NHS over £1bn every year. Therefore, this project addresses a public health issue of great importance, and for which there are large and growing market opportunities.Data from a two-year study on diet and prostate cancer with our proprietary soup product showed that individuals had a reduction in their higher-than- normal blood glucose to levels associated with good health, and remained at this lower level for the duration of the trial. This effect was achieved by consuming just one 300ml portion of soup per week, with no other changes to diet or lifestyle. Blood glucose reduction was not the primary endpoint of this study, and a larger study is needed that is specially focussed on the effect of our food product on blood glucose.The Smarter Food Company (TSFC) has been established to develop this technology and bring to market food products that will assist in the management of blood glucose. TSFC is seeking UKI2S Accelerator funding, matched by private investment, to undertake a human trial of a critical size, and design, to test the hypothesis that a single portion of soup will reduce blood glucose in pre-diabetic individuals to 'healthy' levels. The soup is manufactured from a unique and proprietary broccoli naturally bred to contain very high concentrations of glucoraphanin (VHG). This soup will be used to validate the original findings and confirm the role of glucoraphanin in delivering the desired effect. The successful outcome of the trial will lever substantial private investment to bring this product to market as well as future products. These foods will be marketed to pre-diabetics, health care professionals involved with screening, monitoring and treating T2D, diabetes charities and other relevant NGOs, the health-conscious and worried well, with an approved European Food Standards Agency (EFSA) health claim, and equivalent for other markets. The products will be sold through the major food retailers and by direct online sales.