Transgenerational Consequences of Different Environmental Experiences

该项目旨在提供行为、进化和环境表观遗传学的综合概述。特别是，通过研究为什么生物体的压力相关经历（例如暴露于毒素）可以传递给后代，而不管它似乎会降低健康的影响。它还旨在测试看似有益的非压力相关经验（例如环境丰富）是否可以跨代遗传。该项目包括研究综合（如荟萃分析）和斑马鱼实验，采用尖端的统计、计算和分子方法以及行为分析。此外，预计综合的结果将指导该领域今后的工作。

The project aims to deliver an integrative overview of behavioural, evolutionary and environmental epigenetics. In particular, by studying why stress-related experiences of organisms (e.g. exposure to toxins) can be passed onto the future generations regardless of its seemingly fitness-reducing impacts. It also aims to test if the seemingly beneficial effect of non-stress related experiences (e.g. environmental enrichment) can be inherited transgenerationally. This project involves both research synthesis (e.g. meta-analysis) and experiments on zebrafish employing cutting-edge statistical, computational and molecular methods along with behavioural assays. Also, the outcomes of the synthesis are expected to guide future work in the field.