CORE--PERIPHERAL STEM CELL LABORATORY

外周干细胞核心实验室的主要功能是 作为重建造血过程的管道， 从人骨分离、纯化和/或扩增的干细胞 骨髓、外周血或胎盘血。 该中心实验室将 确保分发给以下组织的所有干细胞材料的质量控制 其他实验室用于研究目的，遵守所有当前和 所有项目的未来监管要求和成本控制，按批量 中央采购协议，并通过有效和综合的 用品的使用。外周干细胞核心实验室（SCL） 将有两个相互作用的化合物，i）单采单位收集 来自正常供体和患者的外周血干细胞（PBSC）， （ii）外周干细胞研究实验室。 单采服务 包括从患者收集外周血干细胞， 同种异体单供者血小板和外周血干细胞采集 用于研究目的的细胞。 服务 在外周干细胞研究实验室提供，包括： i）干细胞群的分离、纯化和离体扩增 ii）干细胞分析 通过流式细胞术和免疫组织化学测定群体，iii） 冷冻保存和储存干细胞群用于研究， iv）分配纯化、扩增和/或冷冻保存的干细胞 五）制定和实施 基因转移到造血干细胞的临床方案 人口。

The primary function of the Peripheral Stem Cell Core Laboratory will be to act as the conduit for the processing of reconstituting hematopoietic stem cells, isolated, purified and/or expanded from either human bone marrow, peripheral or placental blood. This central core laboratory will ensure the quality control of all stem cell materials distributed to other laboratories for research purposes, adherence to all current and future regulatory requirements and cost control for all projects, by bulk central purchasing agreements and by the efficient and integrated utilization of supplies. The Peripheral Stem Cell Core Laboratory (SCL) will have two interactive compounds, i) the Apheresis Unit to collect peripheral blood stem cells (PBSC) from normal donors and patients and ii) the Peripheral Stem Cell Research Laboratory. Apheresis services include the collection of peripheral blood stem cells from patients, the collection of allogeneic single donor platelets and peripheral blood stem cells for research purposes from normal volunteer donors. Services to be provided in the Peripheral Stem Cell Research Laboratory, include: i) Isolation, purification and ex-vivo expansion of stem cell populations from marrow, peripheral and placental blood, ii) Analysis of stem cell populations by flow cytometry and immunohistochemistry, iii) Cryopreservation and storage of stem cell populations for research use, iv) Disbursement of purified, expanded and/or cryopreserved stem cell populations for research purposes and v) Development and implementation of clinical protocols for gene transfer into hematopoietic stem cell populations.