Tunable Laser Source for Confocal Microscopy

共焦显微镜是生物科学中应用最广泛的技术之一。高分辨率图像是通过激光激发光谱中蓝绿色区域的荧光分子而产生的。激光只提供几个固定波长的光，这限制了图像的亮度。M Squared建议通过开发一种覆盖与共焦显微镜相关的整个区域的连续可调的激光光源来克服这一限制。该项目将使用一种新的方法提供一个演示。考虑到市场的规模，未来10年的潜在投资回报率远远超过100倍。M Squared是一家处于早期阶段的企业，其增长高度依赖于技术开发和创新。来自TSB的资金对于抵消开展这一雄心勃勃的研究项目的风险至关重要。

Confocal microscopy is one of the most widely used techniques in biosciences. High resolution images are produced through laser excitation of fluorescent molecules in the blue-green region of the spectrum. Lasers provide light at only a few fixed wavelengths and this limits the brightness of the image. M Squared proposes to overcome this limitation by developing a continuously tuneable laser source covering the whole region of relevance to confocal microscopy. The project will deliver a demonstrator using a novel approach. Given the size of the market, the potential return on investment over 10 years is well in excess of 100 times. M Squared is an early stage business whose growth is highly reliant on technological development and innovation. Funding from the TSB is essential to offset the risks of undertaking this ambitious research project.